The pathogenesis of clinical depression: stressor- and cytokine-induced alterations of neuroplasticity.
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Summary
Depressive illness may be considered a disorder of neuroplasticity as well as one of neurochemical imbalances, and cytokines may act as mediators of both aspects of this illness.
- Type
- review
- Published
- 2005-01-01
- Cited by
- 343
- References
- 267
- OpenAlex
- https://openalex.org/W1987906603
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:24275078
Keywords
Neuroplasticity, Stressor, Neuroscience, Depression (economics), Pathogenesis
References
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- Dissociating anorexia and anhedonia elicited by interleukin-1β: antidepressant and gender effects on responding for "free chow" and "earned" sucrose intake
- Comorbidity of psychiatric disorders and posttraumatic stress disorder.
- The cellular neurobiology of depression
- Maternal care, hippocampal synaptogenesis and cognitive development in rats
Cited by
- [Cognitive disturbances observed in chronic hepatitis C patients during pegylated interferon alpha and ribavirin therapy].
- Metabolic syndrome, activity of the hypothalamic-pituitary-adrenal axis and inflammatory mediators in depressive disorder.
- Moclobemide upregulated Bcl‐2 expression and induced neural stem cell differentiation into serotoninergic neuron via extracellular‐regulated kinase pathway
- Effects of Chronic Stress on Norepinephrine Clearance in the CA3 Region of the Hippocampus
- Psychoneuroimmunology: the example of psoriasis
- Cambios neuroplásticos inducidos por el antidepresivo sertralina en un modelo de depresión en rata
- Effects of biofield vs. mock healing for fatigue, cytokines, and cortisol variability in breast cancer survivors : a randomized, controlled trial
- Antidepressant activity of zinc and magnesium in view of the current hypotheses of antidepressant action.
- Auswirkung von subjektiv empfundenem Stress auf die intrazelluläre Expression von Interleukin 6 der Monozyten und Interferon gamma der Th1-Zellen
- Suppression of piriform cortex activity in rat by corticotropin-releasing factor 1 and serotonin 2A/C receptors
- Airborne inflammatory factors: "from the nose to the brain".
- Early-Life Programming of Later-Life Brain and Behavior: A Critical Role for the Immune System
- A pre-conditioning stress accelerates increases in mouse plasma inflammatory cytokines induced by stress
- PROINFLAMMATORY AND “RESILIENCY” PROTEINS IN THE CSF OF PATIENTS WITH MAJOR DEPRESSION
- Diversity of GABAA receptor synaptic currents on individual pyramidal cortical neurons
- Lipopolysaccharide modulation of thyrotropin-releasing hormone (TRH) and TRH-like peptide levels in rat brain and endocrine organs
- Childhood trauma and parental style: Relationship with markers of inflammation, oxidative stress, and aggression in healthy and personality disordered subjects.
- Assessing the connection between organophosphate pesticide poisoning and mental health: A comparison of neuropsychological symptoms from clinical observations, animal models and epidemiological studies.
- Serotonin gene polymorphisms and lifetime mood disorders in predicting interferon-induced depression in chronic hepatitis C.
- Mechanisms by which exercise promotes hippocampal function in both depressed and non-depressed individuals : a feasibility study
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