Applications of tissue microarray technology in immunohistochemistry: a study on c-kit expression in small cell lung cancer.
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Summary
Tissue microarray technology cannot be a substitute for whole sections in clinical diagnosis of individual cases, and shows a rather poor sensitivity and correlation in the present study.
- Type
- article
- Published
- 2004-11-01
- Cited by
- 17
- References
- 35
- OpenAlex
- https://openalex.org/W1987534396
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:22765142
Keywords
Tissue microarray, Immunohistochemistry, Microarray, DNA microarray, Pathology
References
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- Coexpression of the stem cell factor and the c-kit genes in small-cell lung cancer.
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- Autocrine growth of small cell lung cancer mediated by coexpression of c-kit and stem cell factor.
- Preferential expression of c-kit protooncogene transcripts in small cell lung cancer.
- Expression of c-kit receptor in normal and transformed human nonlymphoid tissues.
- Gentleman R: R: A language for data analysis and graphics
- Reliability of Tissue Microarrays in Detecting Protein Expression and Gene Amplification in Breast Cancer
- HER-2 Analysis in Tissue Microarrays of Archival Human Breast Cancer: Comparison of Immunohistochemistry and Fluorescence In Situ Hybridization
- Tissue microarray technology: validation in colorectal carcinoma and analysis of p53, hMLH1, and hMSH2 immunohistochemical expression
- Biopsy of a biopsy: validation of immunoprofiling in gastric cancer biopsy tissue microarrays
- High-throughput tissue microarray analysis to evaluate genes uncovered by cDNA microarray screening in renal cell carcinoma.
- A case for interstitial cells of Cajal as pacemakers and mediators of neurotransmission in the gastrointestinal tract.
- Recombinant human stem cell factor does exert minor stimulation of growth in small cell lung cancer and melanoma cell lines.
- Inhibition of KIT tyrosine kinase activity: a novel molecular approach to the treatment of KIT-positive malignancies.
- Multiple tissue core arrays in histopathology research: a validation study
- Neuroendocrine expression in metastatic prostate cancer: evaluation of high throughput tissue microarrays to detect heterogeneous protein expression.
- Expression of the proto-oncogenes c-met and c-kit and their ligands, hepatocyte growth factor/scatter factor and stem cell factor, in SCLC cell lines and xenografts.
- Validation of Tissue Microarray Technology in Breast Carcinoma
Cited by
- Angiogenic markers as prognostic factors in non-small cell lung cancer (NSCLC)
- Quantification of prognostic immune cell markers in colorectal cancer using whole slide imaging tumor maps.
- Biomarkers in non-small cell lung carcinoma : methodological aspects and influence of gender, histology and smoking habits on estrogen receptor and epidermal growth factor family receptor signalling
- Tumor hypoxia and hypoxic markers in non-small cell lung cancer
- Tissue microarrays in non-small-cell lung cancer: reliability of immunohistochemically-determined biomarkers.
- Tissue Microarray Applications: A Valuable Clinical and Research Resource
- Negative association of c-fos expression as a favorable prognostic indicator in gastric cancer.
- Effect of distributional heterogeneity on the analysis of tumor hypoxia based on carbonic anhydrase IX
- Proteomic approaches in lung cancer biomarker development
- AlphaB-crystallin: a novel marker of invasive basal-like and metaplastic breast carcinomas.
- Tissue Microarray Validation: A Methodologic Study with Special Reference to Lung Cancer
- A novel tissue array technique for high-throughput tissue microarray analysis — microarray groups
- Tissue microarrays are reliable tools for the clinicopathological characterization of lung cancer tissue.
- Gene Expression Detection Assay for Cancer Clinical Use
- The Determination of Immunomodulation and Its Impact on Survival of Rectal Cancer Patients Depends on the Area Comprising a Tissue Microarray
- Biomarkers in non-small cell lung carcinoma
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