Acute and chronic stress effects on open field activity in the rat: implications for a model of depression.

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Summary

Chronic stressed rats showed endocrine changes similar to those seen in human depressives, and antidepressant treatment with the monoamine oxidase inhibitor pargyline restored the ability of chronically stressed rats to respond actively to stress.

Type
article
Published
1981-06-01
Cited by
911
References
27
Access
Open access

Keywords

Open field, Basal (medicine), Antidepressant, Chronic stress, Psychology

References

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