Bupropion attenuates nicotine abstinence syndrome in the rat
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Summary
These results suggest that these rat models of nicotine dependence and abstinence syndrome may be useful in detecting nicotine abstinence-alleviating effects of potential medications for smoking cessation.
- Type
- article
- Published
- 2006-03-01
- Cited by
- 73
- References
- 55
- OpenAlex
- https://openalex.org/W1986146789
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:25275282
Keywords
Mecamylamine, Bupropion, Nicotine, Abstinence, Nicotine withdrawal
References
- Evidence that the Acute Behavioral and Electrophysiological Effects of Bupropion (Wellbutrin®) Are Mediated by a Noradrenergic Mechanism
- Nicotine dependence: studies with a laboratory model.
- Investigating the actions of bupropion on dependence-related effects of nicotine in rats
- Dramatic decreases in brain reward function during nicotine withdrawal
- Bupropion: a review of its mechanism of antidepressant activity.
- Noncompetitive functional inhibition at diverse, human nicotinic acetylcholine receptor subtypes by bupropion, phencyclidine, and ibogaine.
- Reward and somatic changes during precipitated nicotine withdrawal in rats: centrally and peripherally mediated effects.
- The nitric oxide synthesis inhibitor nitro-L-arginine (L-NNA) attenuates nicotine abstinence syndrome in the rat
- Effect of bupropion on nicotine self-administration in rats
- Nicotine-Induced Changes in Neurotransmitter Levels in Brain Areas Associated with Cognitive Function
- Effects of antidepressant drugs on rats bred for low activity in the swim test.
- The nicotinic antagonist mecamylamine precipitates nicotine abstinence syndrome in the rat
- Bupropion enhances brain reward function and reverses the affective and somatic aspects of nicotine withdrawal in the rat
- Naloxone precipitates nicotine abstinence syndrome in the rat
- Nitric oxide mediates mecamylamine- and naloxone-precipitated nicotine withdrawal.
- Effects of nicotine withdrawal on central dopaminergic systems.
- Smoking, smoking cessation, and major depression.
- Nicotine alleviation of nicotine abstinence syndrome is naloxone-reversible.
- Mecamylamine-precipitated nicotine-withdrawal aversion in rats.
- Naloxone challenge in smokers. Preliminary evidence of an opioid component in nicotine dependence.
Cited by
- Influence of bupropion and calcium channel antagonists on the nicotine-induced memory-related response of mice in the elevated plus maze
- Dopamine D1/5 and D2/3 agonists differentially attenuate somatic signs of nicotine withdrawal in rats.
- Pharmacotherapy for tobacco dependence.
- Bupropion and bupropion analogs as treatments for CNS disorders.
- Neural substrates of psychostimulant withdrawal-induced anhedonia.
- Rodent models of nicotine withdrawal syndrome.
- Efeitos da bupropiona sobre o comportamento sexual, parâmetros espermáticos e fertilidade de ratos machos e sobre a contratilidade do ducto epididimático in vitro
- Identification of Pharmacological and Molecular Mechanisms involved in Nicotine Withdrawal
- Negative affective states and cognitive impairments in nicotine dependence
- PRECLINICAL STUDY: Effects of bupropion, alone or coadministered with nicotine, on social behavior in mice
- Bupropion treatment increases epididymal contractility and impairs sperm quality with no effects on the epididymal sperm transit time of male rats
- Pre- and post-nicotine circadian activity episodes are differentially affected by pharmacological treatments for drug addiction
- The Role of the Habenula in Nicotine Addiction
- Differential Role of Nicotinic Acetylcholine Receptor Subunits in Physical and Affective Nicotine Withdrawal Signs
- Effects of oxytocin on nicotine withdrawal in rats.
- Examining the clinical efficacy of bupropion and nortriptyline as smoking cessation agents in a rodent model of nicotine withdrawal
- Neurochemical and behavioral effects of bupropion and mecamylamine in the presence of nicotine.
- Repetitive Transcranial Magnetic Stimulation of the Dorsolateral Prefrontal Cortex Reduces Nicotine Cue Craving
- Bupropion Differentially Alters the Aversive, Locomotor and Rewarding Properties of Nicotine in CD-1 Mice
- Animal models and treatments for addiction and depression co-morbidity
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