The TIR domain of TIR-NB-LRR resistance proteins is a signaling domain involved in cell death induction.

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Summary

Site-directed mutagenesis of the RPS4 TIR domain identified many loss-of-function mutations but also revealed several gain-of function substitutions, consistent with previous observations that the TIRdomain itself is insufficient to induce cell death upon transient expression.

Type
article
Published
2009-01-08
Cited by
208
References
57

Keywords

Programmed cell death, Biology, Nicotiana benthamiana, Cell biology, Signal transduction

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