Toll-like receptors in systemic autoimmune disease
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Summary
Data are beginning to emerge showing that this is the case that in vivo activation of both autoreactive B cells and plasmacytoid dendritic cells by mammalian TLR ligands translates to an in vivo role in either the initiation or the progression of systemic autoimmune disease.
- Type
- review
- Published
- 2006-11-01
- Cited by
- 1,164
- References
- 138
- Access
- Open access
- OpenAlex
- https://openalex.org/W1985477675
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:2362716
Keywords
Immunology, Biology, Receptor, Immune system, Acquired immune system
References
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- Death, autoantigen modifications, and tolerance
- Stimulation of in vitro murine lymphocyte proliferation by bacterial DNA.
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- The autoantibody repertoire: searching for order
- Heat shock proteins as ligands of toll-like receptors.
- Identification of Small Heat Shock Protein B8 (HSP22) as a Novel TLR4 Ligand and Potential Involvement in the Pathogenesis of Rheumatoid Arthritis1
- Antagonism of immunostimulatory CpG-oligodeoxynucleotides by quinacrine, chloroquine, and structurally related compounds.
- Hydralazine and procainamide inhibit T cell DNA methylation and induce autoreactivity.
- High prevalence of immunoglobulin A antibody against Epstein-Barr virus capsid antigen in adult patients with lupus with disease flare: case control studies.
- Mitogenicity of DNA from different organisms for murine B cells.
- The Molecular Basis for the Lack of Immunostimulatory Activity of Vertebrate DNA1
- An Essential Role of the NF-κB/Toll-Like Receptor Pathway in Induction of Inflammatory and Tissue-Repair Gene Expression by Necrotic Cells1
- Plasmacytoid Dendritic Cells Control TLR7 Sensitivity of Naive B Cells via Type I IFN1
Cited by
- Toll-like Receptor 2 Senses β-Cell Death and Contributes to the Initiation of Autoimmune Diabetes
- Taking a Toll on the bones: Regulation of bone metabolism by innate immune regulators
- Toll-like receptors: lessons to learn from normal and malignant human B cells.
- TLR9 Regulates TLR7- and MyD88-Dependent Autoantibody Production and Disease in a Murine Model of Lupus
- Seladin‐1 is a novel lipopolysaccharide (LPS)‐responsive gene and inhibits the tumour necrosis factor‐α production and osteoclast formation in response to LPS
- Monocyte and Macrophage Abnormalities in Systemic Lupus Erythematosus
- Fibrosis and immune dysregulation in systemic sclerosis.
- CD22 Regulates Adaptive and Innate Immune Responses of B Cells
- Lymphocytes genetically modified to express tumor antigens target dendritic cells in vivo and induce antitumor immunity
- Lipid-derived nanoparticles for immunostimulatory RNA adjuvant delivery
- NKG2D Blockade Inhibits Poly(I:C)-Triggered Fetal Loss in Wild Type but Not IL-10−/− Mice
- FCRL3 promotes TLR9-induced B cell activation and suppresses plasma cell differentiation
- Innate immune viral recognition: relevance to CNS infections.
- The macrophages in rheumatic diseases
- Spatiotemporal Regulation of Hsp90–Ligand Complex Leads to Immune Activation
- Monocyte subsets involved in the development of systemic lupus erythematosus and rheumatoid arthritis
- Apoptotic Regulation of B cell Development and Autoimmunity
- The role of galectin-3 and galectin-9 in the chronic inflammation of rheumatoid arthritis
- The role of nucleosome-induced neutrophil activation in systemic lupus erythematosus
- L' immunologie et la définition de l'identité biologique
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