Increased concentrations of neopterin in carotid atherosclerosis.
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Summary
The data show that the macrophage-derived immune activation marker neopterin is closely correlated with the extent of carotid atherosclerosis, and chronic activation of immune cells, preferentially of macrophages, may play a key role in atherogenesis and/or progression of Atherosclerosis.
- Type
- article
- Published
- 1994-04-01
- Cited by
- 142
- References
- 27
- OpenAlex
- https://openalex.org/W1985046186
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:24315881
Keywords
Neopterin, Medicine, Pathogenesis, Immune system, Internal medicine
References
- Differential expression of the IL-2 receptor subunits, p55 and p75 on various populations of primary peripheral blood mononuclear cells.
- Neopterin : biochemistry, methods, clinical application
- The cytokine handbook
- Neopterin as marker for activation of cellular immunity: immunologic basis and clinical application.
- Gamma-interferon regulates vascular smooth muscle proliferation and Ia antigen expression in vivo and in vitro.
- Measuring the accuracy of diagnostic systems.
- Neopterin levels in patients with coronary artery disease.
- The soluble interleukin-2 receptor: biology, function, and clinical application.
- Secretory products of macrophages.
- Macrophages and atherogenesis.
- Cellular and immunologic features of carotid artery disease in man and experimental animal models.
- The pathogenesis of atherosclerosis--an update.
- Elevated serum neopterin levels in atherosclerosis.
- Neopterin modulates toxicity mediated by reactive oxygen and chloride species
- Estimation of Error Rates in Discriminant Analysis
- Cytokines and growth factors positively and negatively regulate interstitial collagen gene expression in human vascular smooth muscle cells.
- Response of resting human peripheral blood natural killer cells to interleukin 2
- Interleukin 2 pathway is autonomously activated in human T11+3−4−6−8− thymocytes
- Expression of interleukin 2 receptors on activated human B cells
- Determination of neopterin in serum and urine.
Cited by
- 7,8-Dihydroneopterin-mediated protection of low density lipoprotein, but not human macrophages, from oxidative stress
- Heritability of plasma neopterin levels in the Old Order Amish.
- 7,8-dihydroneopterin inhibition of oxidised low density lipoprotein-induced cellular death
- Atherogenesis and atherosclerosis in primary antiphospholipid syndrome
- Macrophage activation is associated with poorer long‐term outcomes in renal transplant patients
- Prognostic value of tryptophan load test followed by serum kynurenine determination. Its comparison with pyridoxal-5-phosphate, kynurenine, homocysteine and neopterin amounts.
- Factors influencing serum neopterin concentrations in a population of blood donors.
- Prostate Cancer Progression and Serum SIBLING (Small Integrin Binding N-Linked Glycoprotein) Levels
- Serologic diagnosis of Hantaan virus infection based on a peptide antigen.
- Bad teeth and myocardial infarction. Biological mechanisms for link.
- Monocyte Count Is a Predictor of Novel Plaque Formation: A 7-Year Follow-up Study of 2610 Persons Without Carotid Plaque at Baseline The Tromsø Study
- HMG-CoA Reductase Inhibitors Are Associated with Decreased Serum Neopterin Levels in Stable Coronary Artery Disease
- Helicobacter pylori and chronic immune activation.
- Pitfalls in the Diagnosis and Therapy of Infections in Elderly Patients – A Mini-Review
- Relations between Concentrations of Asymmetric Dimethylarginine and Neopterin as Potential Risk Factors for Cardiovascular Diseases in Haemodialysis-Treated Patients
- Biochemical profile and survival in nonagenarians.
- Association between Asymmetric Dimethylarginine and Neopterin in Patients with and without Angiographic Coronary Artery Disease
- Similarity Between the Action of Pteridines and Tryptophan Metabolites on Lipid Metabolism
- Urinary Neopterin in Patients with Diabetes Mellitus and Foot Ulcers
- Neopterin and 7,8-Dihydroneopterin Interfere With Low Density Lipoprotein Oxidation Mediated by Peroxynitrite and/or Copper
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