Dissociation of a 110-kD peripheral membrane protein from the Golgi apparatus is an early event in brefeldin A action

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Summary

The dissociation of a 110-kD cytoplasmically oriented peripheral membrane protein from the Golgi apparatus as an early event in BFA action, preceding other morphologic changes suggests that the interaction between the 110- kD protein and the Gol Gi apparatus is dynamic and can be perturbed by metabolic changes or the drug BFA.

Type
article
Published
1990-12-01
Cited by
352
References
25
Access
Open access

Keywords

Brefeldin A, Golgi apparatus, Golgi membrane, Biology, Cytoplasm

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