Gene Expression Profiles in Human Ruptured and Unruptured Intracranial Aneurysms: What Is the Role of Inflammation?
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Summary
Investigation of gene expression patterns of ruptured and unruptured intracranial aneurysms found decreased expression of genes related to muscle system and cell adhesion is important for the development of IA.
- Type
- article
- Published
- 2010-02-01
- Cited by
- 126
- References
- 43
- Access
- Open access
- OpenAlex
- https://openalex.org/W1984645480
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:5921027
Keywords
Medicine, Aneurysm, Radiology, Internal medicine
References
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- Processing of gene expression data generated by quantitative real-time RT-PCR.
- Statistical significance for genomewide studies
- Integrins: the keys to unlocking angiogenesis.
- Genomics of Human Intracranial Aneurysm Wall
- Structural fragility and inflammatory response of ruptured cerebral aneurysms. A comparative study between ruptured and unruptured cerebral aneurysms.
- Inflammation and intracranial aneurysms.
- Psychosocial outcomes for patients and carers after aneurysmal subarachnoid haemorrhage
- Network-based gene expression analysis of intracranial aneurysm tissue reveals role of antigen presenting cells.
- Genesis of Cerebral Aneurysms – An Update
- Complement activation associates with saccular cerebral artery aneurysm wall degeneration and rupture.
- Model-based analysis of oligonucleotide arrays: expression index computation and outlier detection.
- Impact of Monocyte Chemoattractant Protein-1 Deficiency on Cerebral Aneurysm Formation
- A mechanosensitive transcriptional mechanism that controls angiogenesis
- Cell signals transduced by complement.
- The role of C5b-9 terminal complement complex in activation of the cell cycle and transcription
- Hemodynamic shear stress and its role in atherosclerosis.
- Endothelial injury and inflammatory response induced by hemodynamic changes preceding intracranial aneurysm formation: experimental study in rats.
- Vascular extracellular matrix remodeling in cerebral aneurysms.
- Integration of expression profiles and genetic mapping data to identify candidate genes in intracranial aneurysm.
Cited by
- Vascular Smooth Muscle Cells in Cerebral Aneurysm Pathogenesis
- Bioinformatic analysis of gene expression profiling of intracranial aneurysm
- Cellular and molecular mechanisms of saccular intracranial aneurysm formation and rupture
- Intracellular Signaling Pathways in Human Intracranial Aneurysms
- The Identification of Pathway Markers in Intracranial Aneurysm Using Genome-Wide Association Data from Two Different Populations
- Saccular intracranial aneurysm: pathology and mechanisms
- Role of Unphosphorylated Transcription Factor STAT3 in Late Cerebral Ischemia after Subarachnoid Hemorrhage
- Genome-wide microRNA changes in human intracranial aneurysms
- Biology of Intracranial Aneurysms: Role of Inflammation
- Systems biology in unruptured intracranial aneurysm: a metabolomics study in serum for the detection of biomarkers
- MicroRNA/mRNA profiling and regulatory network of intracranial aneurysm
- Identification of crucial genes in intracranial aneurysm based on weighted gene coexpression network analysis
- Etiology and Treatment of Arterial Ischemic Stroke in Children and Young Adults
- Shared associations of nonatherosclerotic, large-vessel, cerebrovascular arteriopathies: considering intracranial aneurysms, cervical artery dissection, moyamoya disease and fibromuscular dysplasia.
- Unusual cause of cerebral vasospasm after pituitary surgery
- Isolation, culture, and characterization of smooth muscle cells from human intracranial aneurysms
- A Case of Neurosyphilis Presenting as a Stroke in a Patient with Human Immunodeficiency Virus Infection
- Role of the complement cascade in cerebral aneurysm formation, growth, and rupture
- Gene Expression Profiling Reveals Distinct Molecular Signatures Associated With the Rupture of Intracranial Aneurysm
- Angiotensin converting enzyme (ACE) insertion/deletion (I/D) polymorphism and circulating ACE levels are not associated with outcome in critically ill septic patients
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