Effect of X‐ and Y‐Box Deletions on the Development of Diabetes in H‐2Eα‐Chain Transgenic Nonobese Diabetic Mice

Keywords

Nod, NOD mice, Transgene, Genetically modified mouse, Major histocompatibility complex

References

• The effect of bone marrow and thymus chimerism between non‐obese diabetic (NOD) and NOD‐E transgenic mice, on the expression and prevention of diabetesAli Emrouznejad, Emmanuel Thanassoulis — 1993
• Quantitative thresholds of MHC class II I-E expressed on hemopoietically derived antigen-presenting cells in transgenic NOD/Lt mice determine level of diabetes resistance and indicate mechanism of protection.Matthew S. Hanson, Marina Ćetković-Cvrlje, Vijayakumar K. Ramiya — 1996
• Aspartate at position 57 of nonobese diabetic I-Ag7 beta-chain diminishes the spontaneous incidence of insulin-dependent diabetes mellitus.Ruby Quartey‐Papafio, Torben Lund, P Chandler — 1995
• IL-12 Administration Reveals Diabetogenic T Cells in Genetically Resistant I-Eα-Transgenic Nonobese Diabetic Mice: Resistance to Autoimmune Diabetes Is Associated with Binding of Eα-Derived Peptides to the I-Ag7 Molecule1Sylvie Trembleau, Silvia Gregori, Giuseppe Penna — 2001
• Restriction fragment length polymorphisms in the major histocompatibility complex of the non-obese diabetic mouse.Torben Lund, Elizabeth Simpson, Anne Cooke — 1990
• Inhibition of Autoimmune Diabetes in Nonobese Diabetic Mice by Transgenic Restoration of H2-E MHC Class II Expression: Additive, But Unequal, Involvement of Multiple APC Subtypes1E. A. Johnson, Pablo A. Silveira, Harold D. Chapman — 2001
• Genetic control of diabetes and insulitis in the nonobese diabetic mouse. Pedigree analysis of a diabetic H-2nod/b heterozygote.Linda S. Wicker, B J Miller, Paul Fischer — 1989
• Breeding of a non-obese, diabetic strain of mice.Susumu Makino, Kikuko Kunimoto, Yoshihiro Muraoka — 1980
• Characterization of pancreatic islet cell infiltrates in NOD mice: effect of cell transfer and transgene expressionL. O’Reilly, Patricia Hutchings, Paul R. Crocker — 1991
• E expression is needed on both bone marrow derived cells and thymic epithelium to increase IL-4 production and achieve protection in NOD bone marrow chimeras.Nina Brenden, Cecilia Rietz, Jan Böhme — 1999
• The NOD mouse: recessive diabetogenic gene in the major histocompatibility complex.Masakazu Hattori, John B. Buse, R. A. JACKSON — 1986
• Immune disturbance and pathogenesis of non-obese diabetes-prone (NOD) mice.Minoru Harada — 2009
• Conserved major histocompatibility complex class II boxes--X and Y--are transcriptional control elements and specifically bind nuclear proteins.A Dorn, Béatrice Durand, Corinne Marfing — 1987
• Prevention of autoimmune insulitis by expression of I–E molecules in NOD miceHirofumi Nishimoto, Hitoshi Kikutani, Ken‐ichi Yamamura — 1987
• MHC-linked protection from diabetes dissociated from clonal deletion of T cells.Jan Böhme, Brigitte Schuhbaur, Osami Kanagawa — 1990
• A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity.Andrew P. Feinberg, Bert Vogelstein — 1983
• The complete nucleotide sequence of the I-E alpha d immune response gene.J. J. Hyldig‐Nielsen, L. Schenning, Ulf Hammerling — 1983
• Direct evidence for the contribution of the unique I-ANOD to the development of insulitis in non-obese diabetic miceToru Miyazaki, Masashi Uno, Masahiro Uehira — 1990
• Prevention of insulin-dependent diabetes mellitus in non-obese diabetic mice by transgenes encoding modified I-A β-chain or normal I-E α-chainTorben Lund, Lorraine A. O’Reilly, Patricia Hutchings — 1990
• The first external domain of the nonobese diabetic mouse class II I-A beta chain is unique.Hans Acha‐Orbea, Hugh O. McDevitt — 1987

Cited by

• Both central and peripheral tolerance mechanisms play roles in diabetes prevention in NOD-E transgenic miceRichard J. Mellanby, Jenny M. Phillips, Nicole M. Parish — 2008
• Dendritic Cell–Dependent In Vivo Generation of Autoregulatory T Cells by Antidiabetogenic MHC Class IISue Tsai, Pau Serra, Xavier Clemente‐Casares — 2013

Related papers

• Studies on the thymus of non-obese diabetic (NOD) mice: effect of transgene expression.Lorraine A. O’Reilly, Don Healey, Elizabeth Simpson — 1994
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• Direct evidence for the contribution of B cells to the progression of insulitis and the development of diabetes in non-obese diabetic mice.Tomoyuki Akashi — 1997
• I-E+ nonobese diabetic mice develop insulitis and diabetesPatricia L. Podolin, A Pressey, Nicole H. DeLarato — 1993
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