Real Options Based Analysis of Optimal Pharmaceutical Research and Development Portfolios
Explore this paper's citation graph
Summary
A method is developed to model new product development as a series of continuation/abandonment options, deciding at each stage in pharmaceutical R&D whether to proceed further or stop development, and a proposed framework provides a road map for future decisions.
- Type
- article
- Published
- 2002-11-14
- Cited by
- 121
- References
- 36
- OpenAlex
- https://openalex.org/W1984578647
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:18657263
Keywords
Portfolio, Abandonment (legal), Stochastic programming, Time horizon, New product development
References
- When Choosing R&D Projects, Go with Long Shots
- Applying ‘Options Thinking’ To R&D Valuation
- Options, Futures, and Other Derivatives
- Portfolio Management in New Product Development: Lessons from the Leaders-I
- Evaluating growth options as sources of value for pharmaceutical research projects
- Real options and interactions with financial flexibility
- DESIGN OF BATCH CHEMICAL PLANTS UNDER MARKET UNCERTAINTY
- Optimization Models for the Scheduling of Testing Tasks in New Product Development
- A Two-Stage Modeling and Solution Framework for Multisite Midterm Planning under Demand Uncertainty
- STRATEGY AND SHAREHOLDER VALUE CREATION: THE REAL OPTIONS FRONTIER
- Real Options: A Practitioner's Guide
- Strategic Supply Chain Optimization for the Pharmaceutical Industries
- A simulation—optimization framework for addressing combinatorial and stochastic aspects of an R&D pipeline management problem
- Returns to R&D on new drug introductions in the 1980s.
- Simultaneous Planning for New Product Development and Batch Manufacturing Facilities
- Success rates for new drugs entering clinical testing in the United States
- Novel Optimization Approach of Stochastic Planning Models
- ECONOMIC ANALYSIS OF R&D PROJECTS: AN OPTIONS APPROACH
- The Pricing of Options and Corporate Liabilities
- A New Look at the Returns and Risks to Pharmaceutical R&D
Cited by
- Applying the concepts of financial options to stimulate vaccine development
- AN INVESTIGATION OF CLINICAL TRIAL SUPPLY CHAINS
- An Aggregation Approach for Capacity Planning under Uncertainty for the Pharmaceutical Industry
- Production of a New Drug: A Sequential Investment ProcessUnder Uncertainty
- Policies and Incentives for Promoting Innovation in Antibiotic Research
- Interdisciplinary research of options theory and management information systems: Review, research issues, and suggestions for future research
- An Open Innovation Decision Support System to Select a Biopharmaceutical R&D Portfolio
- 'Project launch': from research finding to therapeutic product.
- Open innovation: A real option to restore value to the biopharmaceutical R&D
- Using Monte Carlo Simulation to Improve Ceramic R&D Investment Decisions
- A scenario tree approach to multi-period project selection problem using real-option valuation method
- A practical R&D selection model using fuzzy pay-off method
- A hierarchical solution approach for multi-site capacity planning under uncertainty in the pharmaceutical industry
- Enterprise-wide modeling & optimization - An overview of emerging research challenges and opportunities
- Disfunções na implementação da gestão de portfólio de projetos: um estudo quantitativo
- Development of Scenario-Based Models for Optimal Test Scheduling Considering Retest and Outsourcing
- Challenges and opportunities in enterprise-wide optimization in the pharmaceutical industry
- Real-Options-Based Planning Strategies under Uncertainty
- A robust R&D project portfolio optimization model for pharmaceutical contract research organizations
- Real Option Approach for the Management of a New Product Development in the Pharmaceutical Sector
Related papers
- A stochastic look-ahead approach for hurricane relief logistics operations planning under uncertainty
- A Stochastic Lookahead Approach for Hurricane Relief Logistics Operations Planning under Uncertainty
- Study on the Impact of PMO for Multi-Project Management of Contracting Construction Enterprises — Based on Structural Equation Model
- Does project management matter? The relationship between project management effort, complexity, and profitability
- Tactical supply chain planning for a forest biomass power plant under supply uncertainty
- Project portfolio management considering the commitment of agents: A bi-objective model applied to administrative services
- Application of Project Portfolio Management in Electric Power Technical Innovation Project Evaluation