Early, postnatal experience alters hypothalamic corticotropin-releasing factor (CRF) mRNA, median eminence CRF content and stress-induced release in adult rats.
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Summary
Rat pups 2-14 days of age were exposed daily to handling, maternal separation, or were left entirely undisturbed (non-handled; NH), while as adults, MS rats showed increased hypothalamic corticotropin-releasing factor (CRF) mRNA levels compared with NH rats, while CRF mRNA levels in H rats were significantly lower than either MS or NH animals.
- Type
- article
- Published
- 1993-05-01
- Cited by
- 1,758
- References
- 31
- OpenAlex
- https://openalex.org/W1984427714
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:34483994
Keywords
Median eminence, Endocrinology, Internal medicine, Corticosterone, Hypothalamus
References
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