Effect of Polyunsaturated Fatty Acids on Homocysteine Metabolism through Regulating the Gene Expressions Involved in Methionine Metabolism
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Summary
Plasma Hcy was significantly decreased in the 22:6n-3 and conjugated linoleic acid (CLA) groups; mRNA expression of Mthfr was significantly upregulated and Mat1a was upregulated while Cbs was downregulated while downregulated in 18:2n-6 and SO groups.
- Type
- article
- Published
- 2013-05-23
- Cited by
- 31
- References
- 33
- Access
- Open access
- OpenAlex
- https://openalex.org/W1984160437
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:18018790
Keywords
Homocysteine, Methionine, Metabolism, Polyunsaturated fatty acid, Methionine synthase
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Cited by
- Long-term omega-3 fatty acid supplementation prevents expression changes in cochlear homocysteine metabolism and ameliorates progressive hearing loss in C57BL/6J mice.
- Combined omega-3 fatty acids, aerobic exercise and cognitive stimulation prevents decline in gray matter volume of the frontal, parietal and cingulate cortex in patients with mild cognitive impairment
- Genome-wide identification of mononuclear cell DNA methylation sites potentially affected by fish oil supplementation in young infants: A pilot study.
- Tyrosol Attenuates High Fat Diet-Induced Hepatic Oxidative Stress: Potential Involvement of Cystathionine β-Synthase and Cystathionine γ-Lyase
- Dietary methionine supplementation alters the expression of genes involved in methionine metabolism in salmonids
- The CBS/CSE system: a potential therapeutic target in NAFLD?
- Fatty Acid Status and Its Relationship to Cognitive Decline and Homocysteine Levels in the Elderly
- Docosahexaenoic Acid and Cognition throughout the Lifespan
- MTHFR genetic polymorphism increases the risk of preterm delivery.
- Controversy of oral hypoglycemic agents in type 2 diabetes mellitus: Novel move towards combination therapies.
- Nutrition, One-Carbon Metabolism and Neural Tube Defects: A Review
- The n-3 Polyunsaturated Fatty Acids Supplementation Improved the Cognitive Function in the Chinese Elderly with Mild Cognitive Impairment: A Double-Blind Randomized Controlled Trial
- Cochlear Homocysteine Metabolism at the Crossroad of Nutrition and Sensorineural Hearing Loss
- Higher intake of fish and fat is associated with lower plasma s-adenosylhomocysteine: a cross-sectional study.
- The protective effect of polyunsaturated fatty acid intake during pregnancy against embryotoxicity of sodium valproate in mice.
- Comprehensive genetic study of fatty acids helps explain the role of noncoding inflammatory bowel disease associated SNPs and fatty acid metabolism in disease pathogenesis.
- Caloric restriction can affect one-carbon metabolism during pregnancy in the rat: A transgenerational model.
- Parental high dietary arachidonic acid levels modulated the hepatic transcriptome of adult zebrafish (Danio rerio) progeny
- Association of homocysteine with body mass index, blood pressure, HbA1c and duration of diabetes in type 2 diabetics
- Hydrogen sulfide and hepatic lipid metabolism – a critical pairing for liver health
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