Evaluation of a modified micronucleus assay.
Explore this paper's citation graph
Summary
The modified assay revealed apoptosis-induced limitations as recently detected for the maximum micronucleus yield assay, which means that large-scale time kinetics and additional drugs like cytochalasin B can be avoided by changing the evaluation procedure of the conventional micron nucleus assay.
- Type
- article
- Published
- 1996-06-01
- Cited by
- 8
- References
- 25
- OpenAlex
- https://openalex.org/W1984082042
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:20781960
Keywords
Micronucleus test, Micronucleus, Cytochalasin B, Cytochalasin, Ionizing radiation
References
- The production of micronuclei from chromosome aberrations in irradiated cultures of human lymphocytes.
- Significance of the proportion of binucleate cells in the micronucleus assay: a methodological study.
- Detection of apoptosis-associated DNA strand breaks in fine-needle aspiration biopsies by in situ end labeling of fragmented DNA.
- Correlation of micronucleus and apoptosis assays with reproductive cell death.
- The present state and perspectives of micronucleus assay in radiation protection. A review.
- Heterogeneity in the development of apoptosis in irradiated murine tumours of different histologies.
- PROGRAMMED CELL DEATH: CONCEPT, MECHANISM AND CONTROL
- Blood flow modification by nicotinamide and metoclopramide in mouse tumours growing in different sites.
- The micronucleus test.
- Membranes as sensitive targets in thymocyte apoptosis.
- A simplified protocol for the mouse bone marrow micronucleus assay
- Apoptosis induced at different dose rates: implication for the shoulder region of cell survival curves.
- Measurement of micronuclei in lymphocytes.
- Use of the micronucleus assay for the selective detection of radiosensitivity in BUdR-unincorporated cells after pulse-labelling of exponentially growing tumour cells.
- Coming to terms with death: apoptosis in cancer and immune development.
- Micronuclei assay in cytokinesis-blocked binucleated and conventional mononucleated methods in human peripheral lymphocytes.
- EARLY AND LATE CYTOLOGIC EFFECTS OF WHOLE BODY IRRADIATION ON HUMAN MARROW.
- Development of apoptosis in irradiated murine tumors as a function of time and dose.
- Apoptosis in irradiated murine tumors.
- A Monte Carlo/Markov chain model for the association of data for chromosome aberrations and formation of micronuclei.
Cited by
- Correlation of micronucleus and apoptosis assays with reproductive cell death can be improved by considering other modes of death.
- Comparative analysis of apoptosis in HL60 detected by annexin-V and fluorescein-diacetate.
- Testosterone-induced micronuclei and increased nuclear division rate in L929 cell line expressing the androgen receptor.
- Enhanced micronucleus formation in the descendants of gamma-ray-irradiated tobacco cells: evidence for radiation-induced genomic instability in plant cells.
- Radiation therapy induced micronuclei in cervical cancer--does it have a predictive value for local disease control?
- Indications for an active process underlying spontaneous and radiation-induced micronucleation in L929 cells.
- Influence of cell environment on micronucleation in Chinese hamster ovary cells
- Adaption of the Cytokinesis-Block Micronucleus Cytome Assay for Improved Triage Biodosimetry
Related papers
- Antibacterial medicinal plants Equiseti herba and Ononidis radix modulate micronucleus formation in human lymphocytes in vitro.
- Induction of micronuclei by CsCl in vivo and in vitro.
- Genomic instability induced by γ-ray irradiation analyzed by cytokinesis-block MN assay in CHL cell line
- DOSE RESPONSE CURVE FOR MICRONUCLEUS OF CYTOKINESIS-BLOCK METHOD IN HUMAN LYMPHOCYTES AFTER ~(60)Co-GAMMA RAY EXPOSURE
- Increased micronucleus frequency in the progeny of irradiated Chinese hamster cells.
- In vitro micronucleus assay: Method for assessment of nanomaterials using cytochalasin B
- Measurement of micronuclei in lymphocytes.
- The micronucleus assay: an evaluation of its use in determining radiosensitivity in vitro.