Glucosylceramide synthase and glycosphingolipid synthesis.
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Summary
The recent description of a GSL-deficient cell line and isolation of cDNA for GlcCer synthase provide new insights into GSL functions.
- Type
- review
- Published
- 1998-05-01
- Cited by
- 228
- References
- 30
- OpenAlex
- https://openalex.org/W1983571376
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:39590584
Keywords
Glycosphingolipid, Ceramide, Sphingolipid, Biology, Biochemistry
References
- Determination of the intracellular sites and topology of glucosylceramide synthesis in rat liver.
- Targeted mutagenesis of acyl‐lipid desaturases in Synechocystis: evidence for the important roles of polyunsaturated membrane lipids in growth, respiration and photosynthesis.
- Extensive Glycosphingolipid Depletion in the Liver and Lymphoid Organs of Mice Treated with N-Butyldeoxynojirimycin*
- Sphingomyelin synthesis in rat liver occurs predominantly at the cis and medial cisternae of the Golgi apparatus.
- Localization of O-glycan initiation, sphingomyelin synthesis, and glucosylceramide synthesis in Vero cells with respect to the endoplasmic reticulum-Golgi intermediate compartment.
- Topography of glycosyltransferases involved in the initial glycosylations of gangliosides.
- Enzymatic synthesis of ceramide-glucose and ceramide-lactose by glycosyltransferases from embryonic chicken brain.
- The sphingomyelin cycle and the second messenger function of ceramide.
- Topology of glucosylceramide synthesis in Golgi membranes from porcine submaxillary glands.
- Ceramide glucosylation in bean hypocotyl microsomes: evidence that steryl glucoside serves as glucose donor.
- Melanoma antigen expression and metastatic ability of mutant B16 melanoma clones
- Myelination in the absence of galactocerebroside and sulfatide: normal structure with abnormal function and regional instability.
- Accumulation of Glucosylceramides in Multidrug-resistant Cancer Cells*
- Lactosylceramide is synthesized in the lumen of the Golgi apparatus
- Purification and Characterization of UDP-glucose:Ceramide Glucosyltransferase from Rat Liver Golgi Membranes (*)
- Induction of glucosylceramide synthase by synthase inhibitors and ceramide.
- Phylogenetic development of myelin glycosphingolipids.
- Enzymatic formation of plant cerebroside: properties of UDP-glucose: ceramide glucosyltransferase in radish seedlings.
- Induction of Ceramide Glucosyltransferase Activity in Cultured Human Keratinocytes
- CpG-rich islands and the function of DNA methylation
Cited by
- A kibbutz full of lipidsLipids: Regulatory Functions in Membrane Traffic and Cell Development Kfar Blum Kibbutz Guest House, Galilee, Israel, May 10–15, 1998
- Substrate reduction therapy in mouse models of the glycosphingolipidoses.
- Glycosphingolipid Modification: Structural Diversity, Functional and Mechanistic Integration of Diabetes
- Developmental patterns of ceramide glucosyltransferase (GlcT-1) expression in the mouse: in situ hybridization using DIG-labeled RNA probes.
- HCV NS5A and NS5B enhance expression of human ceramide glucosyltransferase gene
- 28 Mouse Models with Gene Deletions of Enzymes and Cofactors Involved in Sphingolipid Synthesis and Degradation
- HETEROGENEITY IN PLATELET EXOCYTOSIS
- Sphingolipid metabolism and analysis in metabolic disease.
- Insulinorésistance musculaire induite par les céramides : étude des mécanismes d'action et de l'implication du transporteur CERT
- Synthesis of o-linked glycoconjugates in the nervous system.
- New developments in treating glycosphingolipid storage diseases.
- Ganglioside Expression During Differentiation of Chick Retinal Cells In Vitro
- Effects of Sugars and Salt on the Production of Glycosphingolipids in Mariannaea Elegans
- Nous ciclitols com a inhibidors de la glucocerebrosidasa. Aplicació al disseny de xaperones farmacològiques per al tractament de la malaltia de Gaucher
- Aproximació terapèutica per a la malaltia de Gaucher basada en xaperones
- Sphingolipids and metabolic disease
- Characterisation of anti-glycan monoclonal antibodies
- Glucosylceramide Synthesized In Vitro from Endogenous Ceramide is Uncoupled from Synthesis of Lactosylceramide in Golgi Membranes from Chicken Embryo Neural Retina Cells
- The Immunological Functions of Saposins
- Lentiviral vectors for gene therapy of Gaucher disease
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