Five SWI/SNF gene products are components of a large multisubunit complex required for transcriptional enhancement.

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Summary

Direct biochemical evidence is provided that all five SWI/SNF polypeptides are components of a large multisubunit complex that coelute from a gel-filtration column and remain associated during an affinity-chromatography step followed by gel filtration.

Type
article
Published
1994-04-12
Cited by
420
References
0
Access
Open access

Keywords

Mutant, Saccharomyces cerevisiae, SWI/SNF, Biology, DNA-binding protein

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