Structure of SARS Coronavirus Spike Receptor-Binding Domain Complexed with Receptor
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Summary
The structure of the RBD suggests ways to make truncated disulfide-stabilized RBD variants for use in the design of coronavirus vaccines.
- Type
- article
- Published
- 2005-09-16
- Cited by
- 2,030
- References
- 51
- OpenAlex
- https://openalex.org/W1982533785
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:12438123
Keywords
Coronavirus, Receptor, Spike Protein, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Protein structure
References
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- ACE2 X-Ray Structures Reveal a Large Hinge-bending Motion Important for Inhibitor Binding and Catalysis
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- Structural Basis for Coronavirus-mediated Membrane Fusion
- A novel coronavirus associated with severe acute respiratory syndrome.
- Receptor-binding domain of SARS-CoV spike protein induces highly potent neutralizing antibodies: implication for developing subunit vaccine
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- Middle East Respiratory Syndrome coronavirus (MERS-CoV): A Review
- Severe Acute Respiratory Syndrome Coronavirus Entry as a Target of Antiviral Therapies
- Structural insights into coronavirus binding to host aminopeptidase N and interaction dynamics
- Preclinical Development Handbook
- Nicotianamine is a novel angiotensin-converting enzyme 2 inhibitor in soybean.
- Development of Instantaneous Protection against SARS-CoV with Implications for Multiple RNA Viruses
- Supramolecular Architecture of the Coronavirus Particle
- Host Entry Factors for Human Coronaviruses
- Bat-to-human: spike features determining ‘host jump’ of coronaviruses SARS-CoV, MERS-CoV, and beyond
- Zoonoses in the Emergence of Human Viral Diseases
- New Insights into the Roles of Metalloproteinases in Neurodegeneration and Neuroprotection
- Protein-Ligand-Wechselwirkungen im Wirkstoffdesign : Ligandbindung an membranständige Proteine in lebenden Zellen und die Identifizierung einer Leitstruktur als entry-Inhibitor der SARS-CoV Infektion
- Adaptive evolution of the spike gene of SARS coronavirus: changes in positively selected sites in different epidemic groups
- The Molecular Biology of Coronaviruses
- Bindungsstudien mit humanen Zellrezeptoren für das SARS-Coronavirus
- Virus Host Interactions in SARS Coronavirus Infection
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