An Empirical Test of Bootstrapping as a Method for Assessing Confidence in Phylogenetic Analysis
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Summary
This work uses computer simulations and a laboratory-generated phylogeny to test bootstrapping results of parsimony analyses, and indicates that any given bootstrap proportion provides an unbiased but highly imprecise measure of repeatability, unless the actual probability of replicating the relevant result is nearly one.
- Type
- article
- Published
- 1993-06-01
- Cited by
- 4,589
- References
- 17
- OpenAlex
- https://openalex.org/W1982447955
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:17210196
Keywords
Bootstrapping (finance), Biology, Phylogenetic tree, Test (biology), Statistics
References
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- Cases in which Parsimony or Compatibility Methods will be Positively Misleading
- Is there something wrong with the bootstrap on phylogenies? A reply to Hillis and Bull
- CONFIDENCE LIMITS ON PHYLOGENIES: AN APPROACH USING THE BOOTSTRAP
- Experimental phylogenetics: generation of a known phylogeny.
- Experimental approaches to phylogenetic analysis
- A Molecular Perspective on Lissamphibian Phylogeny
- Bootstrap Methods: Another Look at the Jackknife
- CONFIDENCE LIMITS ON PHYLOGENIES: THE BOOTSTRAP REVISITED
- The jackknife, the bootstrap, and other resampling plans
- Better Bootstrap Confidence Intervals
- Estimating the reliability of evolutionary trees.
- Signal, noise, and reliability in molecular phylogenetic analyses.
- Statistical properties of bootstrap estimation of phylogenetic variability from nucleotide sequences. I. Four taxa with a molecular clock.
- Testing phylogenetic approaches with empirical data, as illustrated with the parsimony method.
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- Genetic identification of a novel hantavirus of the harvest mouse Reithrodontomys megalotis
- The nuclear gene and cDNAs encoding cytosolic glyceraldehyde-3-phosphate dehydrogenase from the marine red alga Gracilaria verrucosa: cloning, characterization and phylogenetic analysis
- Immunological and Virological Analyses of Persons Infected by Human Immunodeficiency Virus Type 1 while Participating in Trials of Recombinant gp120 Subunit Vaccines
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- Molecular detection of enteroviruses from an outbreak of hand, foot and mouth disease in Malaysia in 1997.
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- Phylogeny of finescale shiners of the genus Lythrurus (Cypriniformes: Cyprinidae) inferred from four mitochondrial genes.
- Multipolar consensus for phylogenetic trees.
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