The leucine-rich repeat as a protein recognition motif.
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Summary
New structural information has increased the understanding of the structural determinants of LRR proteins and the ability to model such proteins with unknown structures, and has shed new light on how these proteins participate in protein-protein interactions.
- Type
- review
- Published
- 2001-12-01
- Cited by
- 1,694
- References
- 47
- OpenAlex
- https://openalex.org/W1981045929
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:41458324
Keywords
Subfamily, Leucine-rich repeat, Biology, Structural motif, Protein structure
References
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- Determination of residues important in hormone binding to the extracellular domain of the luteinizing hormone/chorionic gonadotropin receptor by site-directed mutagenesis and modeling.
- The structure of the mRNA export factor TAP reveals a cis arrangement of a non‐canonical RNP domain and an LRR domain
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- Periodicity of leucine and tandem repetition of a 24-amino acid segment in the primary structure of leucine-rich alpha 2-glycoprotein of human serum.
- Crystal structure of porcine ribonuclease inhibitor, a protein with leucine-rich repeats
- The myosin-I-binding protein Acan125 binds the SH3 domain and belongs to the superfamily of leucine-rich repeat proteins.
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- Glycoprotein hormone receptors: determinants in leucine‐rich repeats responsible for ligand specificity
- Folding and stability of the leucine-rich repeat domain of internalin B from Listeri monocytogenes.
- Characterization of the Brassinosteroid Insensitive 1 Genes of Cotton
- Scribble protein domain mapping reveals a multistep localization mechanism and domains necessary for establishing cortical polarity
- F-box proteins: the key to protein degradation.
- 'Relaxin' the stiffened heart and arteries: the therapeutic potential for relaxin in the treatment of cardiovascular disease.
- Mechanism of auxin perception by the TIR1 ubiquitin ligase
- Comparative sequence analysis of leucine-rich repeats (LRRs) within vertebrate toll-like receptors
- AvrACXcc8004, a Type III Effector with a Leucine-Rich Repeat Domain from Xanthomonas campestris Pathovar campestris Confers Avirulence in Vascular Tissues of Arabidopsis thaliana Ecotype Col-0
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- Solution structure of histone chaperone ANP32B: interaction with core histones H3-H4 through its acidic concave domain.
- Association of TLR polymorphisms with development of tuberculosis in Indonesian females.
- BK potassium channel modulation by leucine-rich repeat-containing proteins
- Integrin triplets of marine sponges in human D2 receptor heteromers
- New insights into the regulation of sexual reproduction in Closterium.
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