Normal cholesterol synthesis in human cells requires functional peroxisomes.

Keywords

Peroxisome, Complementation, Cholesterol, Cholesterol synthesis, Fibroblast

References

• Cholesterol synthesis in rat liver peroxisomes. Conversion of mevalonic acid to cholesterol.Sara L. Thompson, Robert B. Burrows, R. J. Laub — 1987
• Rat liver peroxisomes catalyze the initial step in cholesterol synthesis. The condensation of acetyl-CoA units into acetoacetyl-CoA.Stephen L. Thompson, Skaidrite K. Krisans — 1990
• Rhizomelic chondrodysplasia punctata: biochemical studies of peroxisomes isolated from cultured skin fibroblasts.Inderjit Singh, Wayne S. Stanley, Takashi Hashimoto — 1991
• Nonspecific lipid transfer protein (sterol carrier protein-2) defective in patients with deficient peroxisomes.Yasuyuki Suzuki, Seiji Yamaguchi, Tadao Orii — 1990
• 3-Hydroxy-3-methylglutaryl coenzyme A reductase localization in rat liver peroxisomes and microsomes of control and cholestyramine-treated animals: quantitative biochemical and immunoelectron microscopical analysesG A Keller, Mehran Pazirandeh, Skaidrite K. Krisans — 1986
• Diurnal variation of HMG-CoA reductase activity in rat liver peroxisomes.Nick Rusnak, Skaidrite K. Krisans — 1987
• Presence of individual enzymes of cholesterol biosynthesis in rat liver peroxisomes.Eeva‐Liisa Appelkvist, Michael P. Reinhart, Robert Fischer — 1990
• Hydroxyeicosatetraenoic acid metabolism in cultured human skin fibroblasts. Evidence for peroxisomal beta-oxidation.Joel Gordon, P H Figard, Arthur A. Spector — 1990
• Genetic and Phenotypic Heterogeneity in Disorders of Peroxisome Biogenesis—A Complementation Study Involving Cell Lines from 19 PatientsAdelbert A. Roscher, Sigrid Hoefler, Gerald Höefler — 1989
• Regulation of the mevalonate pathwayJ GOLDSTEIN, Michael S. Brown — 1990
• A rapid procedure for the separation and analysis of metabolites of the sterol and dolichol pathways.R. Kennedy Keller, Steven W. Nellis, Lizette Cuadrado-Simonet — 1989
• Subcellular localization of sterol carrier protein-2 in rat hepatocytes: its primary localization to peroxisomesG A Keller, Terence J. Scallen, Donald D. Clarke — 1989
• Plasma and skin fibroblast C26 fatty acids in infantile Refsum's diseaseA. Poulos, P. Sharp — 1984

Cited by

• Role of wax ester fatty alcohols in chronic blepharitis.Ward E. Shine, James P. McCulley — 1993
• Cholesterol biosynthesis and regulation: role of peroxisomes.Werner J. Kovacs, Skaidrite K. Krisans — 2003
• Peroxisomal Disorders and Regulation of GenesFrank Roels, Myriam Baes, Sylvia De Bie — 2003
• Cholesterol biosynthesis in dermal fibroblasts from patients with metabolic disorders of peroxisomal originErnst Malle, Karl Oettl, Wolfgang Sattler — 1995
• Central role of peroxisomes in isoprenoid biosynthesis.Werner J. Kovacs, Lisa M. Olivier, Skaidrite K. Krisans — 2002
• Comparison of composition and absorption of sugarcane policosanolsChristopher P. F. Marinangeli, Amira Kassis, Deepak Jain — 2007
• Compartmentalization of Cholesterol BiosynthesisLenka Biardi, Skaidrite K. Krisans — 1996
• Metabolic Aspects of Peroxisomal DisordersRonald J. A. Wanders, Gerbert A. Jansen, Carlo W.T. van Roermund — 1996
• Peroxisomes and essential fatty acid deficiencyEric Rabetafika, J.P. Carreau — 1997
• Synthesis of Mevalonate Pathway Lipids in Fibroblasts from Zellweger and X-linked ALD PatientsEeva‐Liisa Appelkvist, Nikolaos Venizelos, Yiyi Zhang — 1999
• Peroxisome biogenesis and the role of protein importLaura‐Anne Brown, Alison Baker — 2003
• Peroxisomes in the apocrine sweat glands of the human axilla and their putative role in pheromone productionGernot Rothardt, Konstantin Beier — 2001
• Cell Compartmentalization of Cholesterol Biosynthesis aSkaidrite K. Krisans — 1996
• Isoprenoid biosynthesis is not compromised in a Zellweger syndrome mouse model.Ilse Vanhorebeek, Myriam Baes, Peter Declercq — 2001
• Tissue specific expression and sequence analysis of a stress responsive gene Bre in adult golden hamster (Mesocricetus auratus)H. K. Poon, John Y.H. Chan, KK Lee — 2004
• Expression of human BRE in multiple isoforms.Arthur Kar Keung Ching, Pik Shan Li, Qing Li — 2001
• Kinetic analysis of butyrylcholinesterase-catalyzed hydrolysis of acetanilides.Patrick Masson, Marie-Thérèse Froment, Émilie Gillon — 2007
• Impaired Cholesterol Synthesis Rate in Fibroblasts and Reduced Cellular Uptake of LDLs Derived from Peroxisome‐deficient Patients Cause Cellular Cholesterol Deficiency in Peroxisome‐deficient Fibroblasts aHanna Mandel, MIRIAM GETSIS, Mira Rosenblat — 1996
• Peroxisomes in adrenal steroidogenesisM. M. Magalhães, Manuel M. Magalhães, Maria C. Magalhães — 1997
• Cholesterol biosynthesis in Zellweger syndrome: Normal activity of mevalonate kinase, mevalonate-5′-pyrophosphate decarboxylase and IPP-isomerase in patients' fibroblasts but deficient mevalonate kinase activity in liverRonald J. A. Wanders, G. J. Romeijn — 1996

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