p53 Arg72Pro polymorphism and risk of colorectal adenoma and cancer
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Summary
The results suggest that Arg72Pro may play a role in the early stages of colorectal neoplasia and possibly in progression to invasive disease, depending on site and sex.
- Type
- article
- Published
- 2006-10-15
- Cited by
- 90
- References
- 34
- Access
- Open access
- OpenAlex
- https://openalex.org/W1980366769
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:24066804
Keywords
Colorectal cancer, Odds ratio, Colorectal adenoma, Genotype, Internal medicine
References
- Role of a p53 polymorphism in the development of human papilloma-virus-associated cancer
- Polymorphism p53 codon‐72 and invasive cervical cancer: a meta‐analysis
- TP53 polymorphisms and lung cancer risk: a systematic review and meta-analysis.
- Two colons‐two cancers: Paradigm shift and clinical implications
- p53 polymorphisms and haplotypes in different ethnic groups.
- A TP53 polymorphism is associated with increased risk of colorectal cancer and with reduced levels of TP53 mRNA
- The p53 pathway
- P53 germ line haplotypes associated with increased risk for colorectal cancer.
- Are there two sides to colorectal cancer?
- A genetic model for colorectal tumorigenesis.
- p53 codon 72 polymorphism and susceptibility malignancy of colorectal cancer in Taiwan
- Is p53 polymorphism maintained by natural selection?
- Are there several colorectal cancers? Epidemiological data.
- Different genetic pathways to proximal and distal colorectal cancer influenced by sex‐related factors
- p53 polymorphic variants at codon 72 exert different effects on cell cycle progression
- Allelic discrimination using fluorogenic probes and the 5' nuclease assay.
- Live or let die: the cell's response to p53
- Characterization of a frequent polymorphism in the coding sequence of the Tp53 gene in colonic cancer patients and a control population
- The codon 72 polymorphic variants of p53 have markedly different apoptotic potential
- Colorectal cancer: evidence for distinct genetic categories based on proximal or distal tumor location.
Cited by
- Association of common WRAP 53 variant with ovarian cancer risk in the Polish population
- TP53 CODON 72 HETEROZYGOSITY MAY PROMOTE MICROSATELLITE INSTABILITY IN SPORADIC COLORECTAL CANCER
- ATM, RAD50 and p53 in breast cancer
- Meta‐analysis of the association between P53 codon 72 polymorphisms and gastric cancer
- Systematic meta-analyses and field synopsis of genetic association studies in colorectal adenomas
- Evidence for an association of TP53 codon 72 polymorphism with sporadic colorectal cancer risk in Isfahan
- [Genetic polymorphism in patients with colorectal and with head and neck cancer].
- The Pro variant of the p53 codon 72 polymorphism is associated with hepatocellular carcinoma in Moroccan population
- p53 Codon 72 Polymorphism and Gastric Cancer Risk in a Chinese Han Population
- P53 codon 72 polymorphism and gastric cancer: A meta‐analysis of the literature
- P53 Codon 72 (Arg72Pro) Polymorphism and Prostate Cancer Risk: Association between Disease Onset and Proline Genotype
- Translating genetic questions into clinical answers in acute myeloid leukemia.
- p53 codon 72 polymorphism in patients affected with ulcerative colitis
- Association of p53 polymorphisms and colorectal cancer: modulation of risk and progression.
- Sensitivity of Immunochemical Fecal Occult Blood Test to Small Colorectal Adenomas
- Genotype and haplotype analysis of cell cycle genes in sporadic colorectal cancer in the Czech Republic
- The MTHFR C677T and ΔDNMT3B C‐149T polymorphisms confer different risks for right‐ and left‐sided colorectal cancer
- TP53 Arg 72Pro and MDM2 SNP309 Polymorphisms and Colorectal Cancer Risk: A West Algerian Population Study
- Association of the p53 codon 72 polymorphism with clinicopathological characteristics of colorectal cancer through mRNA analysis.
- p 53 codon 72 polymorphism in stomach and colorectal adenocarcinomas in Iranian patients.
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