MicroRNA-99 Family Targets AKT/mTOR Signaling Pathway in Dermal Wound Healing
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Summary
Evidence that miR-99 family members contribute to wound healing by regulating the AKT/mTOR signaling is provided.
- Type
- article
- Published
- 2013-05-28
- Cited by
- 186
- References
- 47
- Access
- Open access
- OpenAlex
- https://openalex.org/W1980231360
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:5074940
Keywords
PI3K/AKT/mTOR pathway, microRNA, Protein kinase B, Wound healing, AKT1
References
- Evaluating the MicroRNA Targeting Sites by Luciferase Reporter Gene Assay
- Induction of Specific MicroRNAs Inhibits Cutaneous Wound Healing*
- Microarray analysis of microRNA expression in peripheral blood cells of systemic lupus erythematosus patients
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- Down-regulation of the Rho GTPase signaling pathway is involved in the microRNA-138 mediated inhibition of cell migration and invasion in tongue squamous cell carcinoma
- Topical Insulin Accelerates Wound Healing in Diabetes by Enhancing the AKT and ERK Pathways: A Double-Blind Placebo-Controlled Clinical Trial
- Wound Healing--Aiming for Perfect Skin Regeneration
- MicroRNAs: Novel Regulators Involved in the Pathogenesis of Psoriasis?
- Human Cytomegalovirus Infection Alters the Expression of Cellular MicroRNA Species That Affect Its Replication
- Significance of Plk1 regulation by miR‐100 in human nasopharyngeal cancer
- Reduced miR-100 expression in cervical cancer and precursors and its carcinogenic effect through targeting PLK1 protein.
- MicroRNA-7 targets IGF1R (insulin-like growth factor 1 receptor) in tongue squamous cell carcinoma cells
- A link between mir-100 and FRAP1/mTOR in clear cell ovarian cancer.
- MicroRNA-29, a key regulator of collagen expression in systemic sclerosis.
- miR-196a downregulation increases the expression of type I and III collagens in keloid fibroblasts.
- Restraint stress alters neutrophil and macrophage phenotypes during wound healing
- Morphogenesis in skin is governed by discrete sets of differentially expressed microRNAs
- Evolution of the let-7 microRNA Family
- The modular phosphorylation and activation of p70s6k
Cited by
- Regulation of impaired angiogenesis in diabetic dermal wound healing by microRNA-26a
- The Role of microRNAs in Osteoclastogenesis
- Simulated Microgravity Exerts an Age-Dependent Effect on the Differentiation of Cardiovascular Progenitors Isolated from the Human Heart
- miR-99b suppresses IGF-1R expression and contributes to inhibition of cell proliferation in human epidermal keratinocytes.
- MicroRNA profiling of the pubertal mouse mammary gland identifies miR-184 as a candidate breast tumour suppressor gene
- Not miR-ly micromanagers: the functions and regulatory networks of miRNAs in mammalian skin
- miRNAs in control of oncogenic signaling in breast cancer cells
- RNA sequencing reveals a depletion of collagen targeting microRNAs in Dupuytren’s disease
- Identification of microRNAs regulating adipocyte differentiation via mTOR nutrient-signaling
- mTORC2 promotes cell survival through c-Myc–dependent up-regulation of E2F1
- miRNA-99b-5p suppresses liver metastasis of colorectal cancer by down-regulating mTOR
- miR‐99a Suppresses the Metastasis of Human Non‐Small Cell Lung Cancer Cells by Targeting AKT1 Signaling Pathway
- Identification of MicroRNAs Linked to Regulators of Muscle Protein Synthesis and Regeneration in Young and Old Skeletal Muscle
- Improved repair of dermal wounds in mice lacking microRNA-155
- An updated view on the differentiation of stem cells into endothelial cells
- Expression Profiling of Differentiating Eosinophils in Bone Marrow Cultures Predicts Functional Links between MicroRNAs and Their Target mRNAs
- The co-inertia approach in identification of specific microRNA in early and advanced atherosclerosis plaque.
- Regulation of IGF -1 signaling by microRNAs
- MicroRNA-99 Family Members Suppress Homeobox A1 Expression in Epithelial Cells
- mTORC1 activation blocks BrafV600E-induced growth-arrest, but is insufficient for melanoma formation
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