Structural and Functional Characterization of an Influenza Virus RNA Polymerase-Genomic RNA Complex

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Summary

It is suggested that the interaction with the template is sufficient to induce a significant conformation switch in the polymerase complex, as shown in the case of the monomeric polymerase-vRNA complexes obtained after replication in vivo.

Type
article
Published
2010-08-11
Cited by
48
References
73
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Open access

Keywords

Biology, Polymerase, RNA-dependent RNA polymerase, RNA polymerase I, Molecular biology

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