Evaluation of Antiproliferative, Anti-Type 2 Diabetes, and Antihypertension Potentials of Ellagitannins from Strawberries (Fragaria × ananassa Duch.) Using In Vitro Models
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Summary
The results suggested that the ellagitannins and ellagic acid have good potential for the management of hyperglycemia and hypertension linked to type 2 diabetes and further studies with animal and human models are needed to advance the in vitro assay-based biochemical rationale from this study.
- Type
- article
- Published
- 2010-10-01
- Cited by
- 112
- References
- 80
- Access
- Open access
- OpenAlex
- https://openalex.org/W1979395794
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:25664687
Keywords
Ellagic acid, Fragaria, Chemistry, In vitro, Ellagitannin
References
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Cited by
- In vitro effects of Alba strawberry cultivars on two murine breast cancer cell lines
- A pilot study to investigate bioavailability of strawberry anthocyanins and characterize postprandial plasma polyphenols absorption patterns by Q-TOF LC/MS in humans
- Identification of Ellagitannins and Flavonoids from Eugenia brasilienses Lam. (Grumixama) by HPLC-ESI-MS/MS.
- Antioxidant effects of strawberry fruits at two phenological stages
- Ellagic acid: Pharmacological activities and molecular mechanisms involved in liver protection.
- Early detection and classification of pathogenic fungal disease in post-harvest strawberry fruit by electronic nose and gas chromatography–mass spectrometry
- Ellagic acid identified through metabolomic analysis is an active metabolite in strawberry ('Seolhyang') regulating lipopolysaccharide-induced inflammation.
- Berry polyphenols inhibit α-amylase in vitro: identifying active components in rowanberry and raspberry.
- Strawberry consumption improves plasma antioxidant status and erythrocyte resistance to oxidative haemolysis in humans.
- Identification of bioaccessible and uptaken phenolic compounds from strawberry fruits in in vitro digestion/Caco-2 absorption model.
- Comparative study of chemical and phenolic compositions of two species of jaboticaba: Myrciaria jaboticaba (Vell.) Berg and Myrciaria cauliflora (Mart.) O. Berg
- Biomethanization of waste derived from strawberry processing: advantages of pretreatment
- In vitro bioactivities and phytochemical profile of various parts of the strawberry (Fragaria × ananassa var. Amaou)
- Ellagitannins, ellagic acid and vascular health.
- Berry Polyphenols Inhibit Digestive Enzymes: a Source of Potential Health Benefits?
- Strawberry Polyphenols Attenuate Ethanol-Induced Gastric Lesions in Rats by Activation of Antioxidant Enzymes and Attenuation of MDA Increase
- Strawberry As a Functional Food: An Evidence-Based Review
- Metabolomics unveils urinary changes in subjects with metabolic syndrome following 12-week nut consumption.
- Ellagic acid, an NF-κB inhibitor, ameliorates renal function in experimental diabetic nephropathy.
- The potential impact of strawberry on human health
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