Evidence for using chlorhexidine gluconate preoperative cleansing to reduce the risk of surgical site infection.
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Summary
Evidence-based scientific and clinical studies support two types of CHG application using a standardized, timed process before hospital admission as an effective strategy for reducing the risk of postoperative surgical site infection.
- Type
- article
- Published
- 2010-11-01
- Cited by
- 89
- References
- 33
- Access
- Open access
- OpenAlex
- https://openalex.org/W1979345361
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:42797154
Keywords
Chlorhexidine gluconate, Medicine, Chlorhexidine, Surgical site infection, Infection risk
References
- The effect of washing with chlorhexidine soap on wound infection rate in general surgery. A controlled clinical study.
- Safety and efficacy of the antiseptic chlorhexidine gluconate.
- A comparison of the effects of preoperative whole-body bathing with detergent alone and with detergent containing chlorhexidine gluconate on the frequency of wound infections after clean surgery. The European Working Party on Control of Hospital Infections.
- Corneal edema related to accidental Hibiclens exposure.
- Preoperative shower revisited: can high topical antiseptic levels be achieved on the skin surface before surgical admission?
- Lack of Effect of Antibiotic Resistance on Susceptibility of Microorganisms to Chlorhexidine Gluconate or Povidone Iodine
- Do preoperative chlorhexidine baths reduce the risk of infection after vascular reconstruction?
- Comparative of a new and innovative 2% chlorhexidine gluconate-impregnated cloth with 4% chlorhexidine gluconate as topical antiseptic for preparation of the skin prior to surgery.
- Chlorhexidine vaginal irrigation for the prevention of peripartal infection: a placebo-controlled randomized clinical trial.
- Evaluation of Antiseptic Use in Plastic and Hand Surgery
- Wound infection following vasectomy.
- A randomized trial that compared povidone iodine and chlorhexidine as antiseptics for vaginal hysterectomy.
- Preoperative whole body disinfection--a controlled clinical study.
- Chlorhexidine versus Povidone Iodine in Preventing Colonization of Continuous Epidural Catheters in Children: A Randomized, Controlled Trial
- An Increase in Compliance With the Surgical Care Improvement Project Measures Does Not Prevent Surgical Site Infection in Colorectal Surgery
- Adherence to surgical care improvement project measures and the association with postoperative infections.
- Influence of preoperative showers on staphylococcal skin colonization: a comparative trial of antiseptic skin cleansers.
- Use of Vaginally Administered Chlorhexidine During Labor to Improve Pregnancy Outcomes
- Chlorhexidine-induced degeneration of adrenergic nerves
- Prophylactic Chlorhexidine Oral Rinse Decreases Ventilator-Associated Pneumonia in Surgical ICU Patients
Cited by
- Preoperative risk reduction: strategies to optimize outcomes.
- Periprosthetic joint infection.
- Preventing Surgical Site Infections by Utilizing CHG Wipes for Preoperative Skin Preparation
- Preoperative Skin Antiseptic Preparations and Application Techniques for Preventing Surgical Site Infections: A Systematic Review of the Clinical Evidence and Guidelines
- Pre-Operative Antisepsis Protocol Compliance and the Effect on Bacterial Load Reduction
- Evidence for a Standardized Preadmission Showering Regimen to Achieve Maximal Antiseptic Skin Surface Concentrations of Chlorhexidine Gluconate, 4%, in Surgical Patients.
- No Infection Reduction Using Chlorhexidine Wipes in Total Joint Arthroplasty
- Preoperative Skin Disinfection Methodologies for Reducing Prosthetic Joint Infections
- The value of chlorhexidine gluconate wipes and prepacked washcloths to prevent the spread of pathogens--a systematic review.
- Differences in intraoperative prep solutions: a retrospective chart review.
- Appraisal of guidelines for pre-operative body wash.
- Reducing the risk of surgical site infections: does chlorhexidine gluconate provide a risk reduction benefit?
- To bathe or not to bathe with chlorhexidine gluconate: is it time to take a stand for preadmission bathing and cleansing?
- Patient care interventions to help reduce the risk of surgical site infections.
- Surgical patients: a vulnerable population.
- Economic evaluation of chlorhexidine cloths on healthcare costs due to surgical site infections following total knee arthroplasty.
- Comparison of the efficacy of chlorhexidine gluconate versus povidone iodine as preoperative skin preparation for the prevention of surgical site infections in clean-contaminated upper abdominal surgeries
- Implementation of a surgical comprehensive unit-based safety program to reduce surgical site infections.
- Advance pre-operative chlorhexidine preparation reduces periprosthetic infections following total joint arthroplasty
- Infection prevention methodologies for lower extremity total joint arthroplasty
Related papers
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- EVALUATION OF TOXICITY OF 0.2% CHLORHEXIDINE GLUCONATE AND 0.15% BENZYDAMINE HCL (COMBINED) WITH 0.2% CHLORHEXIDINE GLUCONATE (ALONE) ON ORAL CELL LINE
- The effect of handcream on the antibacterial activity of chlorhexidine gluconate.
- Comparison of the in vivo and in vitro antibacterial properties of providone iodine and chlorhexidine gluconate mouthrinses.
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- Use of Chlorhexidine Preparations in Total Joint Arthroplasty
- A comparison of the effects of preoperative whole-body bathing with detergent alone and with detergent containing chlorhexidine gluconate on the frequency of wound infections after clean surgery. The European Working Party on Control of Hospital Infections.