Modeling Adult Gliomas Using RCAS/t-va Technology.
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Summary
This work demonstrates a versatile and highly reproducible adult mouse model of glioma, which can be easily incorporated into preclinical studies and demonstrated that, in adult mice, gliomas may arise not only when injecting in the subventricular zone but also when injected in the cortex and cerebellum.
- Type
- article
- Published
- 2009-06-01
- Cited by
- 270
- References
- 50
- Access
- Open access
- OpenAlex
- https://openalex.org/W1979240391
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:12590662
Keywords
Subventricular zone, Glioma, Central nervous system, Pathology, Pathophysiology
References
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Cited by
- Macropinocytosis of Bevacizumab by Glioblastoma Cells in the Perivascular Niche Affects their Survival
- DNA-enabled rational design of fluorescence-Raman bimodal nanoprobes for cancer imaging and therapy
- Development of Novel Tools for Radial Glia Lineage Tracing and Modeling Central Nervous System Tumor
- Driving Brain Tumorigenesis: Generation and Biological Characterization of a Mutant IDH1 Mouse Model
- In vivo modeling of malignant glioma: the road to effective therapy.
- Study of molecular mechanisms implicated in the TGF-beta oncogenic effect in Glioma
- Modeling Neural Stem Cell and Glioma Biology
- Characterization of a PDGF-AA Initiated Model of Glioblastoma with Predictable Onset
- Dynamic epigenetic regulation of glioblastoma tumorigenicity through LSD1 modulation of MYC expression
- A novel method of intracranial injection via the postglenoid foramen for brain tumor mouse models.
- Insights Gained from Modeling High-Grade Glioma in the Mouse
- Orthogonal targeting of EGFRvIII expressing glioblastomas through simultaneous EGFR and PLK1 inhibition
- Nouveaux marqueurs des glioblastomes : valeur pronostique, profil d’expression, implication dans la vascularisation et la résistance aux antiangiogéniques
- Ganglioside GD3 Enhances Invasiveness of Gliomas by Forming a Complex with Platelet-derived Growth Factor Receptor α and Yes Kinase*
- Pre-Clinical Models of Diffuse Intrinsic Pontine Glioma
- Fluorine-labeled dasatinib nanoformulations as targeted molecular imaging probes in a PDGFB-driven murine glioblastoma model.
- The TWEAK Receptor Fn14 is a Potential Cell Surface Portal for Targeted Delivery of Glioblastoma Therapeutics
- Modeling PDGF-driven gliomagenesis in the mouse
- Complex Oncogenic Signaling Networks Regulate Brain Tumor-Initiating Cells and Their Progenies: Pivotal Roles of Wild-Type EGFR, EGFRvIII Mutant and Hedgehog Cascades and Novel Multitargeted Therapies
- Loss of CX3CR1 increases accumulation of inflammatory monocytes and promotes gliomagenesis
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