Serial passage of microglial SIV results in selection of homogeneous env quasispecies in the brain.
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Summary
A reproducible infection of the CNS is achieved using a stock of virus obtained by serial passage of microglia-associated SIV, and an enrichment of unique env quasispecies which is maintained through the serial passage was found in the diseased brains.
- Type
- article
- Published
- 1995-10-01
- Cited by
- 54
- References
- 0
- OpenAlex
- https://openalex.org/W1979080661
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:6592845
Keywords
Viral quasispecies, Biology, Virology, Simian immunodeficiency virus, Microglia
References
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