Visceral obesity, metabolic syndrome, insulin resistance and cancer
Explore this paper's citation graph
Summary
Emerging evidence linking visceral adiposity and the metabolic syndrome (MetSyn) with carcinogenesis is presented and it is clear from current research that excess visceral obesity and associated dysmetabolism play a central role in the pathogenesis of certain cancer types.
- Type
- article
- Published
- 2011-11-03
- Cited by
- 310
- References
- 130
- Access
- Open access
- OpenAlex
- https://openalex.org/W1978583076
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:23823989
Keywords
Insulin resistance, Adipose tissue, Metabolic syndrome, Adipokine, Internal medicine
References
- THE PROTECTIVE FUNCTION OF THE GREATER OMENTUM.
- The Omentum
- Metabolic syndrome and leptin are associated with adverse pathological features in male colorectal cancer patients
- Inflammation meets cancer, with NF-κB as the matchmaker
- Local and systemic insulin resistance resulting from hepatic activation of IKK-β and NF-κB
- Clinical study on the correlation between metabolic syndrome and colorectal carcinoma
- Calorie restriction and diet composition modulate spontaneous intestinal tumorigenesis in Apc(Min) mice through different mechanisms.
- The degree of masculine differentiation of obesities: a factor determining predisposition to diabetes, atherosclerosis, gout, and uric calculous disease.
- Demographic variations in the rising incidence of esophageal adenocarcinoma in white males
- Molecular evolution of the metaplasia-dysplasia-adenocarcinoma sequence in the esophagus.
- Visceral Obesity May Affect Oncologic Outcome in Patients with Colorectal Cancer
- Visceral obesity and breast cancer risk
- Adiponectin and adiponectin receptors.
- Insulin therapy and colorectal cancer risk among type 2 diabetes mellitus patients.
- Regulation of adipocytokines and insulin resistance
- Leptin deficiency-induced obesity exacerbates ultraviolet B radiation-induced cyclooxygenase-2 expression and cell survival signals in ultraviolet B-irradiated mouse skin.
- Visceral Obesity and Insulin Resistance as Risk Factors for Colorectal Adenoma: A Cross-Sectional, Case–Control Study
- Overweight, obesity and cancer: epidemiological evidence and proposed mechanisms
- Adipose tissue as an endocrine organ.
- Capacity of adipose tissue to promote growth and metastasis of a murine mammary carcinoma: Effect of estrogen and progesterone
Cited by
- When fat becomes an ally of the enemy: adipose tissue as collaborator in human breast cancer
- Nutritional and metabolic status of breast cancer women.
- Nutritional Approaches for Prevantion and Treatment of Metabolic Syndrome in Adults
- Concise Review: The Obesity Cancer Paradigm: Exploration of the Interactions and Crosstalk with Adipose Stem Cells
- Effect of resistance training on natural killer cell activity in women treated for breast cancer treatment : findings from a randomised controlled trial
- Stromal Cells Derived from Visceral and Obese Adipose Tissue Promote Growth of Ovarian Cancers
- Erratum to: Visceral obesity stimulates anaphase bridge formation and spindle assembly checkpoint dysregulation in radioresistant oesophageal adenocarcinoma
- Lipids generated during acute pancreatitis increase inflammatory status of macrophages by interfering with their M2 polarization.
- Circulating levels of novel adipocytokines in patients with colorectal cancer.
- Low Visceral Fat Content is Associated with Poor Prognosis in a Database of 507 Upper Gastrointestinal Cancers
- Interplay of adipokines and myokines in cancer pathophysiology: Emerging therapeutic implications.
- Attenuation of plasma annexin A1 in human obesity
- Design and rationale of a randomized controlled trial of melatonin supplementation in men and women with the metabolic syndrome
- Patients with nonalcoholic fatty liver disease have higher risk of colorectal adenoma after negative baseline colonoscopy
- Exercise training in breast cancer survivors: a review of trials examining anthropometric and obesity-related biomarkers of breast cancer risk
- Triple-negative breast cancer risk in women is defined by the defect of estrogen signaling: preventive and therapeutic implications
- Body size and breast cancer prognosis in relation to hormone receptor and menopausal status: a meta-analysis
- Association of body mass index and postoperative outcome in patients with colorectal cancer
- Epidemiología del cáncer de mama
- A Twenty-First Century Cancer Epidemic Caused by Obesity: The Involvement of Insulin, Diabetes, and Insulin-Like Growth Factors
Related papers
- The Role of Adipokine in Obesity and Insulin Resistance(Summary)
- [Adipose tissue. Pathophysiology, distribution, sex differences and the role in inflammation and cancerogenesis].
- Adipose tissue inflammation and insulin resistance: all obese humans are not created equal.
- The metabolic syndrome: Insulin resistance
- Metabolic syndrome and insulin resistance in pre-pubertal children with psoriasis
- Study of insulin status in metabolic syndrome in correlation with presence of other risk factors
- Alanine aminotransferase is associated with metabolic syndrome independently of insulin resistance.
- HCV infected patients are “spared” from the metabolic syndrome but not from insulin resistance