Nitric oxide therapy For cardiovascular disease

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Summary

The endogenous NO pathway can now be therapeutically modulated to optimise endothelial or peripheral neuronal vasodilator function by inhibiting PDEV and may be clinically viable through the supplementation of precursors and cofactors of NO synthesis, the upregulation of endothelial NO synthase (eNOS) and the transfection of NOS genes to the vasculature.

Type
article
Published
2001-06-01
Cited by
5
References
64

Keywords

Enos, Downregulation and upregulation, Endothelial dysfunction, Nitric oxide, Nitric oxide synthase

References

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