Topography of the membrane domain of the liver Na+-dependent bile acid transporter.
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Summary
This new method provided evidence for seven membrane segments giving a new model of the membrane domain of this protein and probably the homologous ileal transporter, with H7/H8 as the transport region.
- Type
- article
- Published
- 2005-10-25
- Cited by
- 48
- References
- 0
- OpenAlex
- https://openalex.org/W1978476606
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:38230649
Keywords
Transporter, Chemistry, Bile acid, Membrane, Domain (mathematical analysis)
References
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Cited by
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- Role of the Intestinal Bile Acid Transporters in Bile Acid and Drug Disposition
- Organic Anion Uptake by Hepatocytes
- The role of the sodium-taurocholate cotransporting polypeptide (NTCP) and of the bile salt export pump (BSEP) in physiology and pathophysiology of bile formation.
- A bile acid transporter as a candidate receptor for hepatitis B and D virus entry.
- Mutational Analysis of Uncharged Polar Residues and Proline in the Distal One-Third (Thr130–Pro142) of the Highly Conserved Region of Mouse Slc10a2
- Genetic polymorphisms in Na+-taurocholate co-transporting polypeptide (NTCP) and ileal apical sodium-dependent bile acid transporter (ASBT) and ethnic comparisons of functional variants of NTCP among Asian populations
- Effect of Nine Diets on Xenobiotic Transporters in Livers of Mice
- The new front‐line in hepatitis B/D research: Identification and blocking of a functional receptor
- Regulation of the epithelial sodium channel by phosphatidylinositides: experiments, implications, and speculations
- Membrane topology of human ASBT (SLC10A2) determined by dual label epitope insertion scanning mutagenesis. New evidence for seven transmembrane domains.
- Effects of Ala Substitution for Conserved Cys Residues in Mouse Ileal and Hepatic Na+-Dependent Bile Acid Transporters
- Topology of the Type IIa Na+/Pi Cotransporter
- Importance of uncharged polar residues and proline in the proximal two-thirds (Pro107–Ser128) of the highly conserved region of mouse ileal Na+-dependent bile acid transporter, Slc10a2, in transport activity and cellular expression
- Sodium Taurocholate Cotransporting Polypeptide Mediates Woolly Monkey Hepatitis B Virus Infection of Tupaia Hepatocytes
- Cysteine 96 of Ntcp is responsible for NO-mediated inhibition of taurocholate uptake.
- NTCP and Beyond: Opening the Door to Unveil Hepatitis B Virus Entry
- Xenobiotic, Bile Acid, and Cholesterol Transporters: Function and Regulation
- Cloning and Functional Characterization of Human Sodium-dependent Organic Anion Transporter (SLC10A6)*
- Cytosolic Half of Helix III Forms Substrate Exit Route during Permeation Events of the Sodium/Bile Acid Cotransporter ASBT
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