The effect of carboxymethyl-chitosan on proliferation and collagen secretion of normal and keloid skin fibroblasts.
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Summary
In this study, different molecular weight CM-chitosans were prepared and the effects on the growth and collagen secretion of normal skin fibroblasts and keloid fibroblast were investigated in vitro.
- Type
- article
- Published
- 2002-12-01
- Cited by
- 226
- References
- 26
- OpenAlex
- https://openalex.org/W1978474927
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:21258983
Keywords
Keloid, Fibroblast, Chitosan, Secretion, In vitro
References
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- Studies on Chitin VIII. Some Properties of Water Soluble Chitin Derivatives
- Antibacterial action of chitosan and carboxymethylated chitosan
- Low-molecular-weight chitosans derived from β-chitin : preparation, molecular characteristics and aggregation activity
- Water-soluble chitin as a wound healing accelerator.
- Biochemical composition of the connective tissue in keloids and analysis of collagen metabolism in keloid fibroblast cultures.
- Promotion of calcification on carboxymethylchitin discs.
- Chemical composition of O-(carboxymethyl)-chitins in relation to lysozyme degradation rates
- Evaluation of different absorbance ratios from infrared spectroscopy for analyzing the degree of deacetylation in chitin.
- Collagen gene expression in keloids: analysis of collagen metabolism and type I, III, IV, and V procollagen mRNAs in keloid tissue and keloid fibroblast cultures.
- Altered steady-state ratio of type I/III procollagen mRNAs correlates with selectively increased type I procollagen biosynthesis in cultured keloid fibroblasts.
- Biological activity of chitosan: ultrastructural study.
- Re-examination and further development of a precise and rapid dye method for measuring cell growth/cell kill.
- Bioactive chitin derivatives. Activation of mouse-peritoneal macrophages by O-(carboxymethyl)chitins.
- Biocompatibility of potential wound management products: fungal mycelia as a source of chitin/chitosan and their effect on the proliferation of human F1000 fibroblasts in culture.
- Chitosan--as a biomaterial.
- Collagen biosynthesis by human skin fibroblasts. II. Isolation and further characterization of type I and type III procollagens synthesized in culture.
Cited by
- Structure, morphology and properties of genipin-crosslinked carboxymethylchitosan porous membranes.
- Fabrication of Waterproof, Breathable Composite Liquid Dressing and Its Application in Diabetic Skin Ulcer Repair
- Investigation of Chitosan-glycol/glyoxal as an Injectable Biomaterial for Vocal Fold Tissue Engineering
- Target gene delivery from targeting ligand conjugated chitosan-PEI copolymer for cancer therapy.
- The effect of active ingredient-containing chitosan/polycaprolactone nonwoven mat on wound healing: in vitro and in vivo studies.
- Preparation and Characterization of Carboxymethyl-Functionalized Chitosan Fiber
- Chitin, chitosan and derivatives for wound healing and tissue engineering.
- Evaluation of Chitosan/Aptamer Targeting TGF-β Receptor II Thermo-Sensitive Gel for Scarring in Rat Glaucoma Filtration Surgery.
- Versatile carboxymethyl chitin and chitosan nanomaterials: a review.
- Synthesis, characterization and applications of N-quaternized chitosan/poly(vinyl alcohol) hydrogels.
- Keloids: a new challenge for nutrition.
- One-step synthesis of interpenetrating network hydrogels: Environment sensitivities and drug delivery properties
- Preparation and characterization of carboxymethylated carrageenan modified with collagen peptides.
- Preparation of low-molecular-weight carboxymethyl chitosan and their superoxide anion scavenging activity
- Fibroblast interaction with carboxymethylchitosan-based hydrogels
- Enzymatic synthesis of collagen peptide–carboxymethylated chitosan copolymer and its characterization
- Therapeutic potential of chitosan and its derivatives in regenerative medicine.
- Chitosan-based dressings loaded with neurotensin--an efficient strategy to improve early diabetic wound healing.
- Hydroxyapatite-coated carboxymethyl chitosan scaffolds for promoting osteoblast and stem cell differentiation.
- Synthesis, characterization and biological safety of O-carboxymethyl chitosan used to treat Sarcoma 180 tumor
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