Microglial clearance function in health and disease.
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Summary
Microglial cells are of hematopoietic origin, populate the CNS during early development and form the brain's innate immune cell type and have also pivotal roles during acute and chronic neurodegeneration.
- Type
- article
- Published
- 2009-02-06
- Cited by
- 335
- References
- 67
- OpenAlex
- https://openalex.org/W1978328220
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:22245988
Keywords
Microglia, Neurodegeneration, Innate immune system, Phagocytosis, Neuroinflammation
References
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- UDP acting at P2Y6 receptors is a mediator of microglial phagocytosis
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- Effects of Aging on Neuroprotective and Neurotoxic Properties of Microglia in Neurodegenerative Diseases
Cited by
- Region Specific Effects of Maternal Immune Activation on Offspring Neuroimmune Function
- Development and characterization of a human microglia cell model of HIV-1 infection
- Retinal microglia – A key player in healthy and diseased retina
- The degradation of glial scar and enhancement of chronic intracortical recording electrode performance through the local delivery of dexamethasone and chondroitinase
- Exploring motor neuron degeneration in ALS - prevention by glycoursodeoxycholic acid and signaling to microglia
- Microglia demostrate age-dependent performance and interaction with beta-amyloid peptide
- Eaters of the Dead: How Glial Cells Respond to and Engulf Degenerating Axons in the CNS: A Dissertation
- The Role of Microglial Subsets in Regulating Brain Injury
- K(ATP) Channel blockade instructs microglia to foster brain repair and neurogenesis after stroke
- CARACTERIZACIÓN NEUROHISTOLÓGICA DEL HIPOCAMPO DE RATAS, INYECTADAS CON LA FRACCIÓN 3 DEL EXTRACTO ETANÓLICO DE BUNODOSOMA GRANULIFERA.
- Conséquences de l'invalidation génétique et pharmacologique des récepteurs adénosinergiques A2A dans un modèle de pathologie Tau. Relation avec les aspects neuro-inflammatoires
- Metabolic Syndrome
- Evaluation d'un protocole préclinique d'immunothérapie dirigé contre les tumeurs cérébrales et du potentiel de présentation antigénique croisée des cellules microgliales adultes
- Microglia in the Physiology and Pathology of Brain
- Cellular and Molecular Mechanisms Driving Glial Engulfment of Degenerating Axons: A Dissertation
- Histamine modulates nitric oxide release by microglia and dopaminergic neuronal survival
- E. coli adhérentes et invasives et pathogénèse de la maladie de Crohn : rôle du facteur hypoxique HIF-1
- Lokalisierung und Charakterisierung Foxp3+ regulatorischer T-Zellen bis zu 30 Tage nach mechanischer und ischämischer Läsion des Gehirns
- Ethanol extract of Bupleurum falcatum and saikosaponins inhibit neuroinflammation via inhibition of NF-κB.
- Neuroinflammation: Ways in Which the Immune System Affects the Brain
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