Serum and urinary biochemical markers for knee and hip-osteoarthritis: a systematic review applying the consensus BIPED criteria.
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Summary
International standardization of future investigations should be pursued to obtain more high-quality, homogenous data on the full spectrum of biochemical OA markers.
- Type
- review
- Published
- 2010-05-01
- Cited by
- 193
- References
- 37
- Access
- Open access
- OpenAlex
- https://openalex.org/W1977500066
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:28190496
Keywords
Osteoarthritis, Medicine, Cartilage, Articular cartilage, Urinary system
References
- Correlation of sonographic severity with biochemical markers of synovium and cartilage in knee osteoarthritis patients.
- Relationships between biochemical markers of bone and cartilage degradation with radiological progression in patients with knee osteoarthritis receiving risedronate: the Knee Osteoarthritis Structural Arthritis randomized clinical trial.
- Discovery and development of a type II collagen neoepitope (TIINE) biomarker for matrix metalloproteinase activity: from in vitro to in vivo.
- Crosslinking by advanced glycation end products increases the stiffness of the collagen network in human articular cartilage: a possible mechanism through which age is a risk factor for osteoarthritis.
- Classification of osteoarthritis biomarkers: a proposed approach.
- Molecular basis and clinical use of biochemical markers of bone, cartilage, and synovium in joint diseases.
- Human cartilage glycoprotein 39—biomarker of joint damage in knee osteoarthritis
- Association of Biomarkers With Pre–Radiographically Defined and Radiographically Defined Knee Osteoarthritis in a Population-Based Study
- Uncoupling of type II collagen synthesis and degradation predicts progression of joint damage in patients with knee osteoarthritis.
- Serum biologic markers as predictors of disease progression in osteoarthritis of the knee.
- Analysis of collagenase-cleavage of type II collagen using a neoepitope ELISA.
- The ratio of type II collagen breakdown to synthesis and its relationship with the progression of knee osteoarthritis.
- Urinary TIINE concentrations in a randomized controlled trial of doxycycline in knee osteoarthritis: implications of the lack of association between TIINE levels and joint space narrowing.
- Urinary type II collagen helical peptide (HELIX-II) as a new biochemical marker of cartilage degradation in patients with osteoarthritis and rheumatoid arthritis.
- Diurnal variation of serum and urine biomarkers in patients with radiographic knee osteoarthritis.
- The Helix-II Epitope: A Cautionary Tale from a Cartilage Biomarker Based on an Invalid Collagen Sequence
- Bone marrow abnormalities on magnetic resonance imaging are associated with type II collagen degradation in knee osteoarthritis: a three-month longitudinal study.
- Biomarkers and Surrogate End Points for Fit‐for‐Purpose Development and Regulatory Evaluation of New Drugs
- New serum biochemical markers (Coll 2-1 and Coll 2-1 NO2) for studying oxidative-related type II collagen network degradation in patients with osteoarthritis and rheumatoid arthritis.
- PIIANP and HELIXII diurnal variation.
Cited by
- Osteoarthritis: an update with relevance for clinical practice
- A 12-week randomized, double-blind, placebo-controlled multicenter study of choline-stabilized orthosilicic acid in patients with symptomatic knee osteoarthritis
- Magnetic Capture of a Molecular Biomarker from Synovial Fluid in a Rat Model of Knee Osteoarthritis
- Hip Arthroscopy in Osteoarthritis: A Systematic Review of the Literature
- Tight control and long-term prediction in rheumatoid arthritis
- ALPHA-CTX is associated with subchondral bone turnover and predicts progression of joint space narrowing and osteophytes in osteoarthritis
- Relationship Between Synovial Fluid Biomarkers of Articular Cartilage Metabolism and the Patient’s Perspective of Outcome Depends on the Severity of Articular Cartilage Damage Following ACL Trauma
- Low grade inflammation is associated with lower velocity of sound and broadband ultrasound attenuation in older men, but not with bone loss or fracture risk in a longitudinal aging study.
- Serum hyaluronic acid concentration predicts the progression of joint space narrowing in normal knees and established knee osteoarthritis – a five-year prospective cohort study
- Can We Identify Patients with High Risk of Osteoarthritis Progression Who Will Respond to Treatment? A Focus on Biomarkers and Frailty
- OARSI Clinical Trials Recommendations: Design and conduct of clinical trials for hip osteoarthritis.
- 3D Osteoarthritic Changes in TMJ Condylar Morphology Correlates with Specific Systemic and Local Biomarkers of Disease
- Association of urinary biomarker COLL2-1NO₂ with incident clinical and radiographic knee OA in overweight and obese women.
- Biomarkers of Osteoarthritis: A Review of Recent Research Progress on Soluble Biochemical Markers, Published Patents and Areas for Future Development
- Detection of Urine C2C and Trace Element Level in Patients with Knee Osteoarthritis
- A strategic revolution in HIV and global health.
- Fibulin 3 peptides Fib3-1 and Fib3-2 are potential biomarkers of osteoarthritis.
- Clusters within a wide spectrum of biochemical markers for osteoarthritis: data from CHECK, a large cohort of individuals with very early symptomatic osteoarthritis.
- What Is the Utility of Biomarkers for Assessing the Pathophysiology of Hip Osteoarthritis? A Systematic Review
- Association between serum and urine biomarkers and lumbar spine individual radiographic features: The Johnston County Osteoarthritis Project
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