Triazine dendrimers as drug delivery systems: from synthesis to therapy.
Explore this paper's citation graph
Summary
Triazine adducts with paclitaxel, camptothecin, brefeldin A, and desferrioxamine have been prepared and assessed and show promising activity in vivo.
- Type
- review
- Published
- 2012-06-15
- Cited by
- 146
- References
- 82
- OpenAlex
- https://openalex.org/W1977208317
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:23551270
Keywords
Dendrimer, Triazine, PEGylation, Drug delivery, Camptothecin
References
- LARGE SCALE, GREEN SYNTHESIS OF A GENERATION-1 MELAMINE (TRIAZINE) DENDRIMER
- SYNTHESIS OF 2-[3,3′-DI-(TERT-BUTOXYCARBONYL)-AMINODIPROPYLAMINE]-4,6,-DICHLORO-1,3,5-TRIAZINE AS A MONOMER AND 1,3,5-[TRIS-PIPERAZINE]-TRIAZINE AS A CORE FOR THE LARGE SCALE SYNTHESIS OF MELAMINE (TRIAZINE) DENDRIMERS
- Conformational Analysis of Triazine Dendrimers: Using NMR Spectroscopy To Probe the Choreography of a Dendrimer's Dance.
- Dendrimer biocompatibility and toxicity.
- The Inside Out of Lentiviral Vectors
- Orthogonal, convergent syntheses of dendrimers based on melamine with one or two unique surface sites for manipulation.
- A divergent route to diversity in macromolecules.
- Dendrimers in Supramolecular Chemistry: From Molecular Recognition to Self-Assembly.
- Camptothecins: a review of their development and schedules of administration.
- Biological evaluation of polyester dendrimer: poly(ethylene oxide) "bow-tie" hybrids with tunable molecular weight and architecture.
- Paclitaxel chemotherapy: from empiricism to a mechanism-based formulation strategy
- Dendrimers as carriers for delivery of chemotherapeutic agents.
- Biological Assessment of Triazine Dendrimers as Candidate Platforms for Nanomedicine: Toxicological Profiles, Solution Behavior, Biodistribution, and Drug Release and Efficacy in a PEGylated, Paclitaxel Construct
- The impact of molecular weight and PEG chain length on the systemic pharmacokinetics of PEGylated poly l-lysine dendrimers.
- Modulation of deferoxamine toxicity and clearance by covalent attachment to biocompatible polymers.
- Progress in gene delivery by cationic lipids: guanidinium-cholesterol-based systems as an example.
- Triazine dendrimers as non-viral vectors for in vitro and in vivo RNAi: The effects of peripheral groups and core structure on biological activity
- Synthesis of Odd Generation Triazine Dendrimers Using a Divergent, Macromonomer Approach
- Nonviral vectors for gene delivery.
- Toward the next-generation drug delivery vehicle: synthesis of a dendrimer with four orthogonally reactive groups.
Cited by
- Design, iterative synthesis and structure of novel optically active trispiro-dendritic melamines incorporating ‘open-chain’ versus ‘closed-chain’ serinolic peripheral units
- Perspective: Dendrimer drugs for infection and inflammation.
- Association of the anti-tuberculosis drug rifampicin with a PAMAM dendrimer.
- NOVEL HYDROXYL TERMINATED DENDRIMERS AS POTENTIAL DRUG CARRIERS: SUSTAINED RELEASE, HEMOLYSIS AND CYTOTOXICITY STUDY
- Predicting Adsorption Affinities of Small Molecules on Carbon Nanotubes Using Molecular Dynamics Simulation.
- Fabrication of PEI grafted Fe3O4/SiO2/P(GMA-co-EGDMA) nanoparticle anchored palladium nanocatalyst and its application in Sonogashira cross-coupling reactions
- Triazine-Based Tool Box for Developing Peptidic PET Imaging Probes: Syntheses, Microfluidic Radiolabeling, and Structure–Activity Evaluation
- Oligo(ethylene glycol)-based thermosensitive dendrimers and their tumor accumulation and penetration.
- Nano Pd–Fe3O4@Alg beads: as an efficient and magnetically separable catalyst for Suzuki, Heck and Buchwald–Hartwig coupling reactions
- Production of multi-walled carbon nanotube/poly(aminoamide) dendrimer hybrid and its application to piezoelectric immunosensing for metolcarb
- Oral Anticancer Drugs: Mechanisms of Low Bioavailability and Strategies for Improvement
- Dendrimers in Medicine: Therapeutic Concepts and Pharmaceutical Challenges.
- Supramolecular anticancer drug delivery systems based on linear–dendritic copolymers
- Hydrogen-bonding dramatically modulates the gene transfection efficacy of surface-engineered dendrimers.
- Dendrimer and cancer: a patent review (2006 – present)
- Porphyrins with a carbosilane dendrimer periphery as synthetic components for supramolecular self-assembly.
- Polyester Dendrimers: Smart Carriers for Drug Delivery
- Gadolinium MRI Contrast Agents Based on Triazine Dendrimers: Relaxivity and In Vivo Pharmacokinetics
- Advanced drug delivery systems: Nanotechnology of health design A review
- Impact of pegylation on biopharmaceutical properties of dendrimers
Related papers
- The dendritic effect illustrated with phosphorus dendrimers.
- Dendrimers in medicine and biotechnology. New molecular tools
- The role of the size and number of polyethylene glycol chains in the biodistribution and tumor localization of triazine dendrimers.
- Synthesis of Triazine based Dendrimers: A Mini-Review
- Experimental and computational evidence for an inversion in guest capacity in high-generation triazine dendrimer hosts.
- Conjugated dendrimers with triazine peripheries and a distyrylanthracene core
- Electroluminescence from a new distyrylbenzene based triazine dendrimer