Comparative analysis of the ability of precursor germ cells and epididymal spermatozoa to generate reactive oxygen metabolites.
Explore this paper's citation graph
Summary
It is demonstrated that differentiating male germ cells have the potential to generate ROS, and have implications for the redox regulation of gonadal function and the development of reproductive pathologies involving oxidative stress.
- Type
- article
- Published
- 1997-04-01
- Cited by
- 144
- References
- 51
- OpenAlex
- https://openalex.org/W1976694130
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:31586293
Keywords
Superoxide, Reactive oxygen species, Hydrogen peroxide, Epididymis, Cell biology
References
- Hydrogen peroxide stimulates tyrosine phosphorylation of the insulin receptor and its tyrosine kinase activity in intact cells.
- Genetic evidence for an androgen-regulated epididymal secretory glutathione peroxidase whose transcript does not contain a selenocysteine codon.
- Identification and localization of copper-zinc superoxide dismutase gene expression in rat testicular development.
- Development of an image analysis system to monitor the retention of residual cytoplasm by human spermatozoa: correlation with biochemical markers of the cytoplasmic space, oxidative stress, and sperm function.
- Peroxidative breakdown of phospholipids in human spermatozoa, spermicidal properties of fatty acid peroxides, and protective action of seminal plasma.
- The culture of mouse embryos in vitro.
- Functional expression of NADPH oxidase components (alpha- and beta-subunits of cytochrome b558 and 45-kDa flavoprotein) by intrinsic human glomerular mesangial cells.
- p72syk tyrosine kinase is activated by oxidizing conditions that induce lymphocyte tyrosine phosphorylation and Ca2+ signals.
- Spontaneous lipid peroxidation and production of hydrogen peroxide and superoxide in human spermatozoa. Superoxide dismutase as major enzyme protectant against oxygen toxicity.
- Identification of a superoxide-generating NADPH oxidase system in human fibroblasts.
- Lipid peroxidation and antioxidant enzyme activities in the rat testis after cigarette smoke inhalation or administration of polychlorinated biphenyls or polychlorinated naphthalenes.
- An in vitro promoting role for hydrogen peroxide in human sperm capacitation.
- Characterization and hormonal regulation of 24 kDa protein synthesis by the adult murine epididymis.
- Redox modulation of tyrosine phosphorylation-dependent signal transduction pathways.
- Regulation of indoleamine 2,3-dioxygenase activity in the small intestine and the epididymis of mice.
- Cellular basis of defective sperm function and its association with the genesis of reactive oxygen species by human spermatozoa.
- Formation of Hydrogen Peroxide by Spermatozoa and Its Inhibitory Effect on Respiration
- Differential regulation of cyclic adenosine 3',5'-monophosphate (cAMP) response element-binding protein and cAMP response element modulator messenger ribonucleic acid transcripts by follicle-stimulating hormone and androgen in the adult rat testis.
- Reactive oxygen species generation and human spermatozoa: The balance of benefit and risk
- Hydrogen peroxide is involved in hamster sperm capacitation in vitro.
Cited by
- Leukocytospermia is associated with increased reactive oxygen species production by human spermatozoa.
- Human sperm superoxide anion generation and correlation with semen quality in patients with male infertility.
- The Significance of Testicular Reactive Oxygen Species on Testicular Histology in Infertile Patients
- Decreased spermatogenesis led to alterations of testis-specific gene expression in male mice following nano-TiO2 exposure.
- FSH treatment in infertile males candidate to assisted reproduction improved sperm DNA fragmentation and pregnancy rate
- Polymorphisms of DNA repair genes XRCC1 and LIG4 and idiopathic male infertility
- Scavenger systems and related therapies against lipoperoxidation damage of polyunsaturated fatty acids in spermatozoa.
- Análise comparativa do perfil lipídico do plasma seminal associado ao estresse oxidativo
- Possible redox regulation of sperm motility activation.
- Progesterone‐induced reorganisation of NOX‐2 components in membrane rafts is critical for sperm functioning in Capra hircus
- Composition lipidique des spermatozoides humains et susceptibilité au stress oxydant avant et après migration dans le mucus cervical
- Oxidative stress in sperm biology - a review.
- The effect of reactive oxygen species and smoking on the spermatozoa quality and outcome of patients undergoing IVF/ICSI therapy
- Nitric oxide and superoxide anion production during heparin-induced capacitation in cryopreserved bovine spermatozoa.
- A redox-regulated tyrosine phosphorylation cascade in rat spermatozoa.
- Antioxidant enzyme activity and mRNA expression in reproductive tract of adult male European Bison (Bison bonasus, Linnaeus 1758).
- Total anti‐oxidant status: a biochemical predictor of human male fertility
- Effects of reactive oxygen species from activated leucocytes on human sperm motility, viability and morphology
- PHGPx and spermatogenesis
- Oxidative Stress, Spermatogenesis and Fertility
Related papers
- Regulation of superoxide anion production by NADPH oxidase in monocytes/macrophages: contributions to atherosclerosis.
- Hv1 proton channels are required for high-level NADPH oxidase-dependent superoxide production during the phagocyte respiratory burst
- Homocysteine stimulates NADPH oxidase-mediated superoxide production leading to endothelial dysfunction in rats.
- NADPH-Induced Contractions of Mouse Aorta Do Not Involve NADPH Oxidase: A Role for P2X Receptors
- Homocysteine stimulates phosphorylation of NADPH oxidase p47phox and p67phox subunits in monocytes via protein kinase Cbeta activation.
- [The role of NADPH oxidase in superoxide anion generation in rabbit lens epithelial cells].
- Production of superoxide anion by an NADPH‐oxidase from rat pulmonary macrophages
- Association of Phagocytic NADPH Oxidase Activity With Hypertensive Heart Disease: A Role for Cardiotrophin-1?
- Is the IFN-gamma-induced enhancement of superoxide production in CGD-phagocytes caused by increased expression of the p47-phox cytosolic protein.
- HIV‐1 Nef induces p47phox phosphorylation leading to a rapid superoxide anion release from the U937 human monoblastic cell line