Formation of hematopoietic territories and bone by transplanted human bone marrow stromal cells requires a critical cell density.
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Summary
Evidence is provided that the formation of both hematopoiesis and a mature bone organ is as much a consequence of a sufficiently high local density of bone marrow stromal cells as it is the product of skeletal stem cell action.
- Type
- article
- Published
- 2007-06-01
- Cited by
- 65
- References
- 22
- Access
- Open access
- OpenAlex
- https://openalex.org/W1976209778
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:24002939
Keywords
Stromal cell, Bone marrow, Haematopoiesis, Stem cell, Transplantation
References
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- Stromal stem cells: marrow-derived osteogenic precursors.
- Adipocytic cells cultured from marrow have osteogenic potential.
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- Bone formation in vivo: comparison of osteogenesis by transplanted mouse and human marrow stromal fibroblasts.
- Dilution of human mesenchymal stem cells with dermal fibroblasts and the effects on in vitro and in vivo osteochondrogenesis
- Muscle regeneration by bone marrow-derived myogenic progenitors.
- Blood and bone: two tissues whose fates are intertwined to create the hematopoietic stem-cell niche.
- Recently transposed Alu repeats result from multiple source genes.
- In vivo bone formation by human bone marrow stromal cells: effect of carrier particle size and shape.
- Marrow stromal cells migrate throughout forebrain and cerebellum, and they differentiate into astrocytes after injection into neonatal mouse brains.
- Canine cranial reconstruction using autologous bone marrow stromal cells.
- Marrow stromal cells as a source of progenitor cells for nonhematopoietic tissues in transgenic mice with a phenotype of osteogenesis imperfecta.
- Bone formation in transplants of human bone marrow stromal cells and hydroxyapatite-tricalcium phosphate: prediction with quantitative CT in mice.
- The interplay of osteogenesis and hematopoiesis
- A method for distinguishing human and mouse cells in solid tumors using in situ hybridization.
- EFFECT OF SERUM ON HUMAN BONE MARROW STROMAL CELLS: EX VIVO EXPANSION AND IN VIVO BONE FORMATION
- Single‐Colony Derived Strains of Human Marrow Stromal Fibroblasts Form Bone After Transplantation In Vivo
- Studies on Marrow Histogenesis II. Growth Characteristics of Extramedullary Marrow Autotransplants 1
Cited by
- Bone marrow stem cells in clinical application: harnessing paracrine roles and niche mechanisms.
- Adhesive and mechanical regulation of mesenchymal stem cell differentiation in human bone marrow and periosteum-derived progenitor cells
- Healing capacity of bone marrow mesenchymal stem cells versus platelet-rich fibrin in tibial bone defects of albino rats: an in vivo study
- Direct comparison of current cell-based and cell-free approaches towards the repair of craniofacial bone defects - A preclinical study.
- The pH in the Microenvironment of Human Mesenchymal Stem Cells Is a Critical Factor for Optimal Osteogenesis in Tissue-Engineered Constructs
- In vivo formation of bone and hematopoietic territories by transplanted human bone marrow stromal cells generated in medium with and without osteogenic supplements
- Osteoinduction of biphasic calcium phosphate scaffolds in a nude mouse model
- Comparison of TGFbR2 down-regulation in expanded HSCs on MBA/DBM scaffolds coated by UCB stromal cells
- Bioreactor Systems for Tissue Engineering II
- A clinically relevant model of osteoinduction: a process requiring calcium phosphate and BMP/Wnt signalling
- Platelet lysate coating on scaffolds directly and indirectly enhances cell migration, improving bone and blood vessel formation.
- Human umbilical cord blood-derived stromal cells: Multifaceted regulators of megakaryocytopoiesis
- Late Adherent Human Bone Marrow Stromal Cells Form Bone and Restore the Hematopoietic Microenvironment In Vivo
- Prospective Identification and Skeletal Localization of Cells Capable of Multi-Lineage Differentiation In Vivo
- Repair of a segmental long bone defect in human by implantation of a novel multiple disc graft.
- Human umbilical cord blood-derived stromal cells: a new resource in hematopoietic reconstitution in mouse haploidentical transplantation.
- In vivo alveolar bone regeneration by bone marrow stem cells/fibrin glue composition.
- Pre-clinical studies of bone regeneration with human bone marrow stromal cells and biphasic calcium phosphate
- Creation of New Bone by the Percutaneous Injection of Human Bone Marrow Stromal Cell and HA/TCP Suspensions
- Determining a Clinically Relevant Strategy for Bone Tissue Engineering: An “All-in-One” Study in Nude Mice
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