Selective vulnerability to radiation in the hippocampal dentate granule cells.
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Summary
Vulnerability to radiation existed in the hippocampal dentate granule cells in the hippocampus, and apoptosis in the infantile murine cerebrum after systemic X-ray irradiation was detected.
- Type
- article
- Published
- 2000-05-01
- Cited by
- 76
- References
- 24
- OpenAlex
- https://openalex.org/W1976007412
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:24602175
Keywords
Hippocampal formation, Dentate gyrus, TUNEL assay, Medicine, Agarose gel electrophoresis
References
- A c-Jun dominant negative mutant protects sympathetic neurons against programmed cell death.
- Ischemic delayed neuronal death. A mitochondrial hypothesis.
- Assessment of the long‐term effects of primary radiation. Therapy for brain tumors in children
- Expression of the Apoptosis‐Effector Gene, Bax, Is Up‐Regulated in Vulnerable Hippocampal CA1 Neurons Following Global Ischemia
- Visualization of DNA double strand breaks in the gerbil hippocampal CA1 following transient ischemia.
- Apoptosis in neurological disease.
- Evidence for involvement of Bax and p53, but not caspases, in radiation‐induced cell death of cultured postnatal hippocampal neurons
- Apoptosis by death factor.
- Global ischemia induces apoptosis-associated genes in hippocampus.
- Dexamethasone Does Not Prevent Seven-Day ADX-Induced Apoptosis in the Dentate Gyrus of the Rat Hippocampus.
- Distinct populations of cells in the adult dentate gyrus undergo mitosis or apoptosis in response to adrenalectomy
- Delayed neuronal death in the gerbil hippocampus following ischemia.
- Morphometric study of the interphase nucleus in some radiosensitive and radioresistant mammalian cells.
- Hippocampal dentate granule cell degeneration after adrenalectomy in the rat is not reversed by dexamethasone.
- MK-801, an antagonist of NMDA receptors, inhibits injury-induced c-fos protein accumulation in rat brain.
- Radiation-induced DNA damage in tumors and normal tissues. II. Influence of dose, residual DNA damage and physiological factors in oxygenated cells.
- Adrenalectomy‐induced granule cell degeneration in the rat hippocampal dentate gyrus: Characterization of an in vivo model of controlled neuronal death
- p53 is required for radiation-induced apoptosis in mouse thymocytes
- p53‐deficient mice are protected against adrenalectomy‐induced apoptosis
- The long-term side effects of radiation therapy for benign brain tumors in adults.
Cited by
- Caractérisation des facteurs de régulation de la prolifération des cellules souches neurales dans le cerveau adulte
- Evaluating the regulation and function of adult mouse hippocampal neurogenesis induced from running
- Emerging Treatment Paradigms in Radiation Oncology
- Effects of Low Level Radiation exposure on Neurogenesis and Cognitive Function: Mechanisms and Prevention
- A radiation-induced hippocampal vascular injury surrogate marker predicts late neurocognitive dysfunction
- Chronic 835-MHz radiofrequency exposure to mice hippocampus alters the distribution of calbindin and GFAP immunoreactivity.
- Optimizing patient positioning for intensity modulated radiation therapy in hippocampal-sparing whole brain radiation therapy.
- Radiation Therapy in the Management of Patients With Limited Brain Metastases
- Distribution of brain metastases in relation to the hippocampus: implications for neurocognitive functional preservation.
- Radiation response of neural precursor cells.
- Glycogen Synthase Kinase 3 Beta Inhibitors Protect Hippocampal Neurons from Radiation-Induced Apoptosis by Regulating MDM2/p53 Pathway
- Emerging Roles of Glycogen Synthase Kinase 3 in the Treatment of Brain Tumors
- Evaluation of hippocampus dose for patients undergoing intensity-modulated radiotherapy for nasopharyngeal carcinoma.
- Neuropsychological outcome after fractionated stereotactic radiotherapy (FSRT) for base of skull meningiomas: a prospective 1-year follow-up.
- Time-dependent involvement of adult-born dentate granule cells in behavior
- Why Avoid the Hippocampus? A Comprehensive Review
- Conventional radiation therapy for brain metastases
- Extreme sensitivity of adult neurogenesis to low doses of X-irradiation.
- Lithium treatment prevents neurocognitive deficit resulting from cranial irradiation.
- Proliferating cell nuclear antigen positive cells in the hippocampal subgranular zone decline after irradiation in a rodent model
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