Synopsis of some recent tactical application of bioisosteres in drug design.

Keywords

Citation, Phone, Computer science, Library science, Social media

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• Development of ligands for the validation of the lysophosphatidic acid receptor LPAInês Gil — 2014
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• Application of the guanidine–acylguanidine bioisosteric approach to NPY Y2 receptor antagonists: bivalent, radiolabeled and fluorescent pharmacological toolsNikola Pluym — 2011
• Synthesis and structure-activity relationships of inhibitors of bacterial hyaluronidase: An approach to obtain compounds with drug-like propertiesCarolin Meyer — 2014
• Practical strategies for small-molecule probe development in chemical biology.Jonathan E. Hempel, Charles C. Hong — 2015
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• Refining the chemical toolbox to be fit for educational and practical purpose for drug discovery in the 21st Century.Marco L. Lolli, Sarah Narramore, Colin W. G. Fishwick — 2015
• Design, Synthesis, and Evaluation of Functionalized Chroman-4-one and Chromone Derivatives. Somatostatin receptor agonists and Sirt2 inhibitorsMaria Fridén‐Saxin — 2012
• Stereochemical properties of N-benzoylated carbazole derivativesSusumu Kayama, Hidetsugu Tabata, Yuka Takahashi — 2015
• 先导化合物结构优化策略（一）——改变代谢途径提高代谢稳定性王江, 柳红 — 2013
• Copper-Promoted Trifluoromethanesulfonylation and Trifluoromethylation of Arenediazonium Tetrafluoroborates with NaSO2CF3.Ke Zhang, Xiu‐Hua Xu, Feng‐Ling Qing — 2015
• Cytotoxicity of Thiazolidinedione-, Oxazolidinedione- and Pyrrolidinedione-Ring Containing Compounds in HepG2 CellsAlyssa Marie Keil, Douglas M. Frederick, Erina Y. Jacinto — 2015
• Palladium-Catalyzed Monofluoromethylation of Arylboronic Esters with Fluoromethyl Iodide.Jingyu Hu, Bing Gao, Lingchun Li — 2015
• Selective synthesis of fluoroalkyl-containing multisubstituted benzenes through Co-mediated [2+2+2] cycloaddition reaction with fluoroalkylated alkynesYukiho Sakaguchi, Yoshitomo Nakazaki, Kazuki Moriyasu — 2015
• 6-Arylpyrazine-2-carboxamides: A New Core for Trypanosoma brucei Inhibitors.Raphaël Rahmani, Kung Ban, Amy J. Jones — 2015

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