Neoadjuvant chemotherapy plus cystectomy compared with cystectomy alone for locally advanced bladder cancer.
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Summary
Using neoadjuvant methotrexate, vinblastine, doxorubicin, and cisplatin followed by radical cystectomy increases the likelihood of eliminating residual cancer in the Cystectomy specimen and is associated with improved survival among patients with locally advanced bladder cancer.
- Type
- article
- Published
- 2003-08-28
- Cited by
- 2,584
- References
- 18
- Access
- Open access
- OpenAlex
- https://openalex.org/W1975918912
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:42913929
Keywords
Cystectomy, Medicine, Bladder cancer, Vinblastine, Urology
References
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- Sequential treatment assignment with balancing for prognostic factors in the controlled clinical trial.
- Cancer Statistics, 2001
- Adjuvant and neoadjuvant chemotherapy for invasive bladder cancer
- Treatment of advanced bladder cancer with combined preoperative irradiation and radical cystectomy versus radical cystectomy alone: a phase III intergroup study.
- Maintenance bacillus Calmette-Guerin immunotherapy for recurrent TA, T1 and carcinoma in situ transitional cell carcinoma of the bladder: a randomized Southwest Oncology Group Study.
- Preliminary results of M-VAC (methotrexate, vinblastine, doxorubicin and cisplatin) for transitional cell carcinoma of the urothelium.
- Contemporary cystectomy with pelvic node dissection compared to preoperative radiation therapy plus cystectomy in management of invasive bladder cancer.
- A randomized comparison of cisplatin alone or in combination with methotrexate, vinblastine, and doxorubicin in patients with metastatic urothelial carcinoma: a cooperative group study.
- Integrated therapy for locally advanced bladder cancer: final report of a randomized trial of cystectomy plus adjuvant M-VAC versus cystectomy with both preoperative and postoperative M-VAC.
- Neoadjuvant cisplatin, methotrexate, and vinblastine chemotherapy for muscle-invasive bladder cancer: a randomised controlled trial. International collaboration of trialists.
Cited by
- Predicting response to methotrexate, vinblastine, doxorubicin, and cisplatin neoadjuvant chemotherapy for bladder cancers through genome-wide gene expression profiling.
- Laparoscopic lymph node dissection in urologic cancer.
- Systemic chemotherapy for urothelial cancer.
- Importance of node dissection in relation to neoadjuvant and adjuvant therapy.
- Neoadjuvant chemotherapy for bladder transitional cell carcinoma: a new standard of care?
- Urinary diversion: options, patient selection, and outcomes.
- Long‐term follow up of patients with invasive bladder carcinoma receiving combined cisplatin‐based intra‐arterial chemotherapy and radiotherapy
- Urothelial carcinoma of the bladder: definition, treatment and future efforts
- Neoadjuvant Chemotherapy for Invasive Bladder Cancer
- The impact of smoking on pathologic response to neoadjuvant cisplatin-based chemotherapy in patients with muscle-invasive bladder cancer
- Actionable mutations in muscle-invasive bladder cancer
- The future of bladder cancer care in the USA
- Controversies in the treatment of invasive urothelial carcinoma: a case report and review of the literature
- Neoadjuvant chemotherapy administration and time to cystectomy for muscle-invasive bladder cancer: An evaluation of transitions between academic and community settings
- Robot‐assisted radical cystectomy
- Platinum Concentration and Pathologic Response to Cisplatin-Based Neoadjuvant Chemotherapy in Muscle-Invasive Bladder Cancer
- Toward personalized management in bladder cancer: the promise of novel molecular taxonomy
- Expression of PDL1 (B7-H1) Before and After Neoadjuvant Chemotherapy in Urothelial Carcinoma.
- Bladder cancer: Present and future.
- Atezolizumab in invasive and metastatic urothelial carcinoma
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