Electron microscopic study of the ethidium bromide-DNA complex.
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Summary
The ethidium bromide-DNA complex has been studied by electron microscopy and in agreement with the fact that the dye intercalates between nucleotide pairs, the DNA molecule increases in length at saturation.
- Type
- article
- Published
- 1971-09-14
- Cited by
- 64
- References
- 4
- OpenAlex
- https://openalex.org/W1975703176
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:45839949
Keywords
Ethidium bromide, DNA, Intercalation (chemistry), Chemistry, Molecule
References
- The interaction of closed circular DNA with intercalative dyes. I. The superhelix density of SV40 DNA in the presence and absence of dye.
- A Molecular Model for the Interaction of Ethidium Bromide with Deoxyribonucleic Acid
- Structural considerations in the interaction of DNA and acridines.
- Supercoiling of polyoma virus DNA measured by its interaction with ethidium bromide.
Cited by
- The sense of naturally occurring superhelices and the unwinding angle of intercalated ethidium.
- Chemical relaxation kinetic studies of E. coli RNA polymerase binding to poly [d(A--T)] using ethidium bromide as a fluorescence probe.
- Molecular Studies of R Factor Compatibility Groups
- Binding of ethidium bromide to ribosomal RNA. Absorption, fluorescence, circular and electric dichroism study.
- Transduction and Plasmid Deoxyribonucleic Acid Analysis in a Multiply Antibiotic-Resistant Strain of Staphylococcus epidermidis
- Plasmid in Bacillus pumilus and the Enhanced Sporulation of Plasmid-Negative Variants
- Visualization of drug--nucleic acid interactions at atomic resolution. VI. Structure of two drug--dinucleoside monophosphate crystalline complexes, ellipticine--5-iodocytidylyy (3'-5') guanosine and 3,5,6,8-tetramethyl-N-methyl phenanthrolinium--5-iodocytidylyl (3'-5') guanosine.
- Agarose Gel Electrophoresis
- Drug-nucleic acid interaction: X-ray crystallographic determination of an ethidium-dinucleoside monophosphate crystalline complex, ethidium: 5-iodouridylyl(3'-5')adenosine.
- ESR study of intercalation: quantitative evaluation of drug-DNA binding through competition with a spin-labeled 9-aminoacridine.
- Terminal stages of SV40 DNA replication proceed via multiply intertwined catenated dimers.
- Spectroscopic Visualization of Right- and Left-Handed Helical Alignments of DNA in Chiral Vortex Flows
- Electron microscopy of membrane-associated folded chromosomes of Escherichia coli
- Studies on the interactions of nogalamycin with duplex DNA.
- The gel electrophoresis of DNA.
- DNA analysis on electrophoretic microchips: Effect of operational variables
- Dehydrated circular DNA: electron microscopy of ethanol-condensed molecules.
- Optimization in sample stacking for high-performance capillary electrophoresis
- The blue-green alga agmenellum quadruplicatum contains covalently closed DNA circles.
- Mitochondrial DNA from Drosophila melanogaster.
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