HIV/AIDS: in search of an animal model.
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Summary
The uses and limitations of existing models and recent advances that might lead to better animal models for HIV/AIDS are discussed.
- Type
- review
- Published
- 2007-08-01
- Cited by
- 95
- References
- 49
- OpenAlex
- https://openalex.org/W1975240882
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:574631
Keywords
Simian immunodeficiency virus, Virology, Human immunodeficiency virus (HIV), Animal model, Virus
References
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- High-Titer Immune Responses Elicited by Recombinant Vaccinia Virus Priming and Particle Boosting Are Ineffective in Preventing Virulent SIV Infection
- Animal models of AIDS
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- Protection of macaques against vaginal transmission of a pathogenic HIV-1/SIV chimeric virus by passive infusion of neutralizing antibodies
- Mucosal AIDS vaccine reduces disease and viral load in gut reservoir and blood after mucosal infection of macaques
- Characterization of infectious molecular clones of simian immunodeficiency virus (SIVmac) and human immunodeficiency virus type 2: persistent infection of rhesus monkeys with molecularly cloned SIVmac
- A chimeric simian/human immunodeficiency virus expressing a primary patient human immunodeficiency virus type 1 isolate env causes an AIDS-like disease after in vivo passage in rhesus monkeys
- Human neutralizing monoclonal antibodies of the IgG1 subtype protect against mucosal simian–human immunodeficiency virus infection
- Genital mucosal transmission of simian immunodeficiency virus: animal model for heterosexual transmission of human immunodeficiency virus
- Generation of a chimeric human and simian immunodeficiency virus infectious to monkey peripheral blood mononuclear cells
- Characterization of Simian-Human Immunodeficiency Virus Envelope Glycoprotein Epitopes Recognized by Neutralizing Antibodies from Infected Monkeys
- Intrinsic immunity: a front-line defense against viral attack
- Isolation of T-cell tropic HTLV-III-like retrovirus from macaques.
- Disseminated and sustained HIV infection in CD34+ cord blood cell-transplanted Rag2−/−γc−/− mice
- Animal model for the therapy of acquired immunodeficiency syndrome with reverse transcriptase inhibitors.
- SIV/HIV Recombinants and Their Use in Studying Biological Properties
- Human immunodeficiency virus infection of human-PBL-SCID mice.
- Reduced Virus Load in Rhesus Macaques Immunized with Recombinant gp160 and Challenged with Simian Immunodeficiency Virus
Cited by
- Pneumocystis Colonization and Chronic Obstructive Pulmonary Disease in a Simian Model of HIV Infection
- Rapid adversarial co-evolution of viruses and cellular restriction factors.
- Experimental primates and non-human primate (NHP) models of human diseases in China: current status and progress.
- Regulation of immunity to visceral Leishmania in a non-human primate model of infection
- SIV Escape from Immune Recognition Due to Selection Pressure of Immunodominant CD8+ Epitope GAG-CM9 and TRIM5 Restriction Sites
- In‐vivo stimulation of macaque natural killer T cells with α‐galactosylceramide
- Why Primate Models Matter
- Development of allosteric biosensors for the diagnosis of infectious diseases
- Needlestick over the Pacific Ocean! Now What?
- Macaca fascicularis are highly susceptible to an RT‐SHIV following intravaginal inoculation: a new model for microbicide evaluation
- A Monoclonal Antibody Selection for Immunohistochemical Examination of Lymphoid Tissues From Non-human Primates
- An overview of intracellular interactions between immunodeficiency viruses and their hosts
- Genetic Knockouts Suggest a Critical Role for HIV Co-Receptors in Models of HIV gp120-Induced Brain Injury
- Rhesus M1.3S Cells Suitable for Biological Evaluation of Macaque-Tropic HIV/SIV Clones
- Animal models in virus research: their utility and limitations
- HIV-1 Induced AIDS in Monkeys
- Latest animal models for anti-HIV drug discovery
- A Variant Macaque-Tropic Human Immunodeficiency Virus Type 1 Is Resistant to Alpha Interferon-Induced Restriction in Pig-Tailed Macaque CD4+ T Cells
- Chronic parasite infections cause immune changes that could affect successful vaccination.
- Adaptation to the Interferon-Induced Antiviral State by Human and Simian Immunodeficiency Viruses
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