MicroRNAs in cancer: biomarkers, functions and therapy.
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Summary
The potential applications of microRNAs for the clinical assessment of patient outcome in cancer, as well as in cancer monitoring and therapy are reviewed.
- Type
- review
- Published
- 2014-08-01
- Cited by
- 1,997
- References
- 80
- Access
- Open access
- OpenAlex
- https://openalex.org/W1974254202
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:11397858
Keywords
microRNA, Cancer therapy, Cancer, Medicine, Biomarker
References
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- Development of a lung cancer therapeutic based on the tumor suppressor microRNA-34
- The LCS6 polymorphism in the binding site of let-7 microRNA to the KRAS 3′-untranslated region: its role in the efficacy of anti-EGFR-based therapy in metastatic colorectal cancer patients
- ADAR1 forms a complex with Dicer to promote microRNA processing and RNA-induced gene silencing
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- microRNA-451: A conditional switch controlling glioma cell proliferation and migration
- Repression of Dicer is associated with invasive phenotype and chemoresistance in ovarian cancer
- Attenuated adenosine-to-inosine editing of microRNA-376a* promotes invasiveness of glioblastoma cells.
- Human RNA methyltransferase BCDIN3D regulates microRNA processing
- Bioinformatic analysis of barcoded cDNA libraries for small RNA profiling by next-generation sequencing
- MicroRNA signatures: clinical biomarkers for the diagnosis and treatment of breast cancer.
- MicroRNA-146a directs the symmetric division of Snail-dominant colorectal cancer stem cells
Cited by
- Two less common human microRNAs miR-875 and miR-3144 target a conserved site of E6 oncogene in most high-risk human papillomavirus subtypes
- Clinical significance of microRNAs in chronic and acute human leukemia
- Investigating the mechanism of hepatocellular carcinoma progression by constructing genetic and epigenetic networks using NGS data identification and big database mining method
- Recent advances in biosensor development for the detection of cancer biomarkers.
- Mesenchymal stem cell transplantation in tight-skin mice identifies miR-151-5p as a therapeutic target for systemic sclerosis
- microRNA-664 enhances proliferation, migration and invasion of lung cancer cells.
- MicroRNA-31 suppresses the self-renewal capability of α2δ1+ liver tumor-initiating cells by targeting ISL1
- Regulation of antitumor miR‐144‐5p targets oncogenes: Direct regulation of syndecan‐3 and its clinical significance
- Long non-coding RNA H19, and not microRNA miR-326, is over-expressed and predicts survival in glioblastoma.
- The potential role of miRNAs in multiple myeloma therapy
- miRNA arm switching identifies novel tumour biomarkers
- Testicular Cancer Biomarkers: A Role for Precision Medicine in Testicular Cancer
- Breast cancer detection using targeted plasma metabolomics.
- miR-29a-3p inhibits growth, proliferation, and invasion of papillary thyroid carcinoma by suppressing NF-κB signaling via direct targeting of OTUB2
- A two-microRNA-based signature predicts first-line chemotherapy outcomes in advanced colorectal cancer patients
- Towards control of cellular decision-making networks in the epithelial-to-mesenchymal transition
- Nanoarchitecture Frameworks for Electrochemical miRNA Detection.
- The untranslated regions of mRNAs in cancer
- miR-6716-5p promotes metastasis of colorectal cancer through downregulating NAT10 expression
- Thiol functionalised gold nanoparticles loaded with methotrexate for cancer treatment: From synthesis to in vitro studies on neuroblastoma cell lines.
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