Accumulation of cholesteryl esters and triglycerides in cultured macrophages incubated with plasma very low density lipoproteins from rats fed on casein or soybean protein diets containing moderate levels of cholesterol.
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Summary
A significant and apparently saturable cellular accumulation of cholesteryl esters as well as triglycerides was produced by VLDL from cholesterol-fed rats, which differed between groups of rats fed on different types of dietary protein with higher proportions of apo C's in the casein- fed rats.
- Type
- article
- Published
- 1986-11-01
- Cited by
- 7
- References
- 26
- OpenAlex
- https://openalex.org/W1974090916
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:23484311
Keywords
Very low-density lipoprotein, Casein, Cholesterol, Cholesteryl ester, Intermediate-density lipoprotein
References
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- Release of arachidonic acid from 1-alkyl-2-acyl-sn-glycero-3-phosphocholine, a precursor of platelet-activating factor, in rat alveolar macrophages.
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- Effect of dietary proteins on hepatic and plasma lipids, and some properties of major plasma lipoprotein fractions during dietary-induced hypercholesterolemia in male rats.
- Nonenzymatic Glucosylation of Low-Density Lipoprotein Alters Its Biologic Activity
- Apolipoprotein B is structurally and metabolically heterogeneous in the rat.
- Effect of apoproteins on hepatic uptake of triglyceride emulsions in the rat.
- Effects of high cholesterol diets on rat plasma lipoproteins and lipoprotein-cell interactions.
- Alterations of the plasma lipoproteins and apoproteins following cholesterol feeding in the rat.
- Transfer of proteins across membranes. I. Presence of proteolytically processed and unprocessed nascent immunoglobulin light chains on membrane-bound ribosomes of murine myeloma
- Lipoprotein metabolism in the macrophage: implications for cholesterol deposition in atherosclerosis.
- Lipoprotein lipase secretion by human monocyte-derived macrophages.
- A rapid and simple method for measurement of total protein in very low density lipoproteins by the Lowry assay.
Cited by
- Effect of metoprolol on plasma lipids and arterial intimal lipid deposition in spontaneously hypertensive rats.
- The effects of dietary protein on the fatty acid composition and Δ6 desaturase activity of rat hepatic microsomes
- Differences in the underlying mechanisms of cholesterol- and casein-induced hypercholesterolemia in rabbit and rat.
- Dietary protein and fatty acid composition of liver lipids in the rat.
- Reduction of mortality in the Stockholm Ischaemic Heart Disease Secondary Prevention Study by combined treatment with clofibrate and nicotinic acid.
- Metabolism of very low density lipoproteins in rats with isotretinoin (13-cis retinoic acid)-induced hyperlipidemia.
- Effect of Lipoproteins and Platelets on Macrophage Cholesterol Metabolism
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