A protein that binds specifically to the M-line of skeletal muscle is identified as the muscle form of creatine kinase.

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Summary

Immunofluorescent studies showed that antiserum against MM-creatine kinase was bound in a regular pattern at the centers of the A-band regions of isolated myofibrils, showing conclusively that the M-line protein and MM- Creatine kinases are identical.

Type
article
Published
1973-03-01
Cited by
221
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0
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Open access

Keywords

Creatine kinase, Antiserum, Myofibril, Molecular biology, Skeletal muscle

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