A fluorescence in situ hybridization (FISH) microfluidic platform for detection of HER2 amplification in cancer cells.
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Summary
The microfluidic system developed herein is promising for rapid, automatic diagnosis of HER2-related diseases by detecting the HER2 gene with minimal consumption of samples and reagents and has a great potential for future pharmacogenetic diagnostics and therapy.
- Type
- article
- Published
- 2015-07-15
- Cited by
- 36
- References
- 29
- OpenAlex
- https://openalex.org/W1973846682
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:206168747
Keywords
Fluorescence in situ hybridization, In situ hybridization, Biomarker, Cancer, Fish
References
- Absence of chromosome 17 polysomy in breast cancer: analysis by CEP17 chromogenic in situ hybridization and multiplex ligation-dependent probe amplification
- Preparation of a human DOPA decarboxylase cDNA probe by PCR and its assignment to chromosome 7.
- Fluorescence in situ hybridization: powerful molecular tool for cancer prognosis.
- An on-chip Cell-SELEX process for automatic selection of high-affinity aptamers specific to different histologically classified ovarian cancer cells.
- A pneumatic micropump incorporated with a normally closed valve capable of generating a high pumping rate and a high back pressure
- A novel integrated microfluidic platform to perform fluorescence in situ hybridization for chromosomal analysis
- Test in the Emerging Intellectual Property Business
- Immunological method for mapping genes on Drosophila polytene chromosomes.
- Fluorescence in situ hybridization with Alu and L1 polymerase chain reaction probes for rapid characterization of human chromosomes in hybrid cell lines.
- Fluorescence in situ hybridization with human chromosome-specific libraries: detection of trisomy 21 and translocations of chromosome 4.
- Size-controlled synthesis of gold nanoparticles using a micro-mixing system
- The HER2 Receptor in Breast Cancer: Pathophysiology, Clinical Use, and New Advances in Therapy
- Metaphase FISH on a Chip: Miniaturized Microfluidic Device for Fluorescence in situ Hybridization
- Fabrication of a New Micro Bio Chip and Flow Cell Cytometry System using MEMS Technology
- Pneumatic micropumps with serially connected actuation chambers
- FISH-based determination of HER2 status in circulating tumor cells isolated with the microfluidic CEE™ platform.
- Impact of HER-2 overexpression/amplification on the prognosis of gastric cancer patients undergoing resection: a single-center study of 1,036 patients.
- Fluorescence in situ Hybridization Analysis of Circulating Tumor Cells in Metastatic Prostate Cancer
- Relationship between pathological features, HER2 protein expression and HER2 and CEP17 copy number in breast cancer: biological and methodological considerations
- Preimplantation genetic diagnosis using fluorescent in situ hybridization for cancer predisposition syndromes caused by microdeletions.
Cited by
- Recent advances in biosensor development for the detection of cancer biomarkers.
- Fluorescence In situ Hybridization: Cell-Based Genetic Diagnostic and Research Applications
- Microfluidics-assisted fluorescence in situ hybridization for advantageous human epidermal growth factor receptor 2 assessment in breast cancer
- Microfluidic-assisted chromogenic in situ hybridization (MA-CISH) for fast and accurate breast cancer diagnosis
- A sensitive electrochemical aptasensing platform based on exonuclease recycling amplification and host-guest recognition for detection of breast cancer biomarker HER2
- Breast cancer HER2 analysis by extra-short incubation microfluidics-assisted fluorescence in situ hybridization (ESIMA FISH)
- Rapid micro fluorescence in situ hybridization in tissue sections
- Microfluidic approaches for cell-based molecular diagnosis.
- Fluorescence in situ hybridization (FISH): History, limitations and what to expect from micro-scale FISH?
- MicroRNA amplification and detection technologies: opportunities and challenges for point of care diagnostics
- Next generation sequencing for the water industry
- Impedimetric aptasensing of the breast cancer biomarker HER2 using a glassy carbon electrode modified with gold nanoparticles in a composite consisting of electrochemically reduced graphene oxide and single-walled carbon nanotubes
- Improvement of fluorescence-based microfluidic DNA analyzers
- FLUORESCENCE IN SITU HYBRIDIZATION (FISH) ENHANCEMENT USING MICROFLUIDIC FLOW FOR AN ACCURATE, FAST AND ECONOMICAL ASSESSMENT OF HER2 STATUS IN BREAST CANCER
- FISH and chips: a review of microfluidic platforms for FISH analysis
- High throughput physiological micro-models for in vitro pre-clinical drug testing: a review of engineering systems approaches
- Clinical Application of Multiple Reaction Monitoring-Mass Spectrometry to Human Epidermal Growth Factor Receptor 2 Measurements as a Potential Diagnostic Tool for Breast Cancer Therapy.
- Influence of patient age and oral contraceptives on different variables in breast cancer
- Can microRNA become next-generation tools in molecular diagnostics and therapeutics? A systematic review
- Cytogenetic and Biochemical Genetic Techniques for Personalized Drug Therapy in Europe
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