Rapid formation of plasma protein corona critically affects nanoparticle pathophysiology.

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Summary

It is shown that label-free snapshot proteomics can be used to obtain quantitative time-resolved profiles of human plasma coronas formed on silica and polystyrene nanoparticles of various size and surface functionalization.

Type
article
Published
2013-10-01
Cited by
2,098
References
49

Keywords

Nanoparticle, Surface modification, Biophysics, Nanotoxicology, Biological fluids

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