Induction of corticotropin-releasing hormone gene expression by glucocorticoids: implication for understanding the states of fear and anxiety and allostatic load.

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Summary

The excess glucocorticoids and CRH, and the state of anticipatory anxiety, contribute to allostatic load, a new term that refers to the wear and tear on the body and brain arising from attempts to adapt to adversity.

Type
review
Published
1998-04-01
Cited by
436
References
137
Access
Open access

Keywords

Stria terminalis, Amygdala, Anxiety, Allostatic load, Corticotropin-releasing hormone

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