Expression of human soluble TRAIL in Chlamydomonas reinhardtii chloroplast
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Summary
The experimental results demonstrated the possibility of using transgenic chloroplasts of green alga as bioreactors for production of biopharmaceuticals.
- Type
- article
- Published
- 2006-07-30
- Cited by
- 54
- References
- 22
- OpenAlex
- https://openalex.org/W1973781323
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:94553262
Keywords
Chlamydomonas reinhardtii, Chloroplast, Molecular biology, Western blot, Biology
References
- How TRAIL Kills Cancer Cells, But Not Normal Cells
- High-yield production of a human therapeutic protein in tobacco chloroplasts
- Engineering the chloroplast genome: techniques and capabilities for chloroplast transformation in Chlamydomonas reinhardtii.
- Transgenic plastids in basic research and plant biotechnology.
- Chloroplast-derived vaccine antigens and other therapeutic proteins.
- Three new yellow loci in Chlamydomonas reinhardtii
- Expression of the native cholera toxin B subunit gene and assembly as functional oligomers in transgenic tobacco chloroplasts
- Prospects for molecular farming in the green alga Chlamydomonas.
- Expression of an antimicrobial peptide via the chloroplast genome to control phytopathogenic bacteria and fungi.
- Transgenic expression of aminoglycoside adenine transferase in the chloroplast: a selectable marker of site-directed transformation of chlamydomonas.
- Expression and assembly of a fully active antibody in algae
- Expression of a foreign gene in Chlamydomonas reinhardtii chloroplast.
- Renilla luciferase as a vital reporter for chloroplast gene expression in Chlamydomonas
- Induction of Apoptosis by Apo-2 Ligand, a New Member of the Tumor Necrosis Factor Cytokine Family*
- Expression of human antibodies in eukaryotic micro-algae.
- Plant-based production of biopharmaceuticals.
- Development of a GFP reporter gene for Chlamydomonas reinhardtii chloroplast.
- Light-independent chlorophyll biosynthesis: involvement of the chloroplast gene chlL (frxC).
- Identification and characterization of a new member of the TNF family that induces apoptosis.
- Expression of tetanus toxin Fragment C in tobacco chloroplasts.
Cited by
- Perspective for the use of genetic transformants in order to enhance the synthesis of the desired metabolites: Engineering chloroplasts of microalgae for the production of bioactive compounds.
- Molecular Farming in Plants: Recent Advances and Future Prospects
- Genetic engineering of green microalgae for the production of biofules and high value products
- Chlamydomonas as a model for biofuels and bio-products production
- Biological potential of microalgae in China for biorefinery-based production of biofuels and high value compounds.
- Chlamydomonas reinhardtii chloroplasts as protein factories.
- Robust Expression and Secretion of Xylanase1 in Chlamydomonas reinhardtii by Fusion to a Selection Gene and Processing with the FMDV 2A Peptide
- Photosynthetic biomanufacturing in green algae; production of recombinant proteins for industrial, nutritional, and medical uses
- Expression of bovine lactoferrin N-lobe by the green alga, Chlorella vulgaris
- Transgenic Expression of a Bacterial Thermophilic Amylase in the Chlamydomonas reinhardtii Chloroplast to Facilitate Algal Biofuel Production
- Unconventional microbial systems for the cost-efficient production of high-quality protein therapeutics.
- Microalgae as platforms for production of recombinant proteins and valuable compounds: progress and prospects
- A novel expression platform for the production of diabetes-associated autoantigen human glutamic acid decarboxylase (hGAD65)
- Plant biofarming: Novel insights for peptide expression in heterologous systems
- Expression of human soluble tumor necrosis factor (TNF)-related apoptosis-inducing ligand in transplastomic tobacco
- Production of therapeutic proteins in the chloroplast of Chlamydomonas reinhardtii
- Method to assemble and integrate biochemical pathways into the chloroplast genome of Chlamydomonas reinhardtii
- Expanding the spectral palette of fluorescent proteins for the green microalga Chlamydomonas reinhardtii.
- Micro-algae come of age as a platform for recombinant protein production
- Developing a transgenic microalga to enhance algal starch utilization for fuel and chemical production
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