Mitochondrial Respiratory Chain Deficiency inCaenorhabditis elegans Results in Developmental Arrest and Increased Life Span*

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Summary

The common phenotype induced by the mutations and drugs suggests that the L3-to-L4 transition may involve an energy-sensing developmental checkpoint, and it is predicted that L3 arrest will be characteristic of mutations in these genes.

Type
article
Published
2001-08-24
Cited by
155
References
49
Access
Open access

Keywords

Biology, Caenorhabditis elegans, Mitochondrial biogenesis, Respiratory chain, ATP synthase

References

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