Blood-brain barrier delivery.
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Summary
Brain drug development programs of the future need to be re-configured so that drugs are formulated to enable transport into the brain via endogenous BBB transporters.
- Type
- review
- Published
- 2007-01-01
- Cited by
- 1,137
- References
- 74
- OpenAlex
- https://openalex.org/W1973544766
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:32180575
Keywords
Blood–brain barrier, Endogeny, Transporter, Drug delivery, Mammalian brain
References
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- Antibody directed against mannan of the Mycobacterium tuberculosis cell envelope provokes blood-brain barrier breakdown.
- Uptake of Melatonin into the Cerebrospinal Fluid After Nasal and Intravenous Delivery: Studies in Rats and Comparison with a Human Study
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- Neuroprotection in Transient Focal Brain Ischemia After Delayed Intravenous Administration of Brain-Derived Neurotrophic Factor Conjugated to a Blood-Brain Barrier Drug Targeting System
- Blood-Brain Barrier Permeation: Molecular Parameters Governing Passive Diffusion
- The distribution and elimination of methotrexate in mouse blood and brain after concurrent administration of polysorbate 80
- Up‐Regulation of Blood‐Brain Barrier Short‐Form Leptin Receptor Gene Products in Rats Fed a High Fat Diet
- Changes in the permeability of the blood-brain barrier following sodium dodecyl sulphate administration in the rat
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